Disease Information for Botulism, infant: Definition

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  • Botulism is also due to decreased release of acetylcholine from presynaptic terminals; Toxin produced by Clostridium botulinum spores irreversibly binds to the terminal cholinergic nerve twigs. The result is profound weakness, sometimes with respiratory compromise; A mild decremental response to repetitive nerve stimulation occurs, but a pronounced incremental response occurs after exercise or with rapid (20-Hz) repetitive nerve stimulation [Adapted Family Practice Notebook 2004]

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