Disease Information for Atypical Hemolytic Uremic Syndrome: Definition

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  • Atypical Hemolytic Uremic Syndrome; Inherited Hemolytic-Uremic Syndrome; aHUS; Atypical hemolytic uremic syndrome (aHUS) is an extremely rare group of disorders of the kidneys; It is a distinctly different illness from hemolytic uremic syndrome caused by the bacterium E coli 0157:h7 (Stx HUS); While Stx HUS typically is preceded by a flu-like illness and is associated with that particular strain of E coli bacterium, there is substantial evidence that aHUS is a genetic disorder; Atypical hemolytic uremic syndrome may become a chronic condition, and patients with aHUS may experience repeated attacks of the disorder; When children with Stx HUS recover from the life-threatening initial episode, they are likely to respond well to supportive treatment and to make a good recovery; Children with aHUS are much more likely to develop chronic serious complications such as kidney failure and severe high blood pressure------------------[NORD 2005]--------------

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