Disease Information for Antiphospholipid Syndrome/APLS: Definition

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  • Cause unknown autoimmune antibody activation of platelets with recurrent thrombosis of placenta, large arteries with spontaneous thrombosis, with CVA often embolic; overlaps with some collagen disorders; causes recurrent miscarriage; occasionally triggered by contraceptive medication; antiphospholipids and anticardiolipin levels increased with thrombocytopenia

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