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Disease Information for Deferoxamine (Desferal) Administration/Toxicity

Clinical Manifestations

Signs & Symptoms

Cold clammy skin

Oliguria/Decreased urine output

URINE Color Red

Cold clammy pale status

Collapse/Prostration

Associated Diseases & Rule outs

Associated Disease & Complications

Acute anuria/renal failure

Acute Renal Failure

Anaphylaxis, generalized

Azotemia/Acute

Cataract

Deferoxamine (Desferal) effect/toxicity

Drug Allergy

Drug Induced Infusion Reaction

Mucor disseminated/vasculitis

Mucor/lung infection

Mucormycosis

Mucormycosis, rhinocerebral (Phycomycosis)

Respiratory distress (adult) syndrome

Disease Mechanism & Classification

Drugs

DRUG/Antidote/specific medication (example)

DRUG/Chelating agent (example)

Process

PROCESS/Medication/Drug (CONFIRM dose/before treatment)

Toxin

TOXIN/Lethal possible

Synonyms

Synonym

1 Amino 6,17 dihydroxy 7,10,18,21 tetraoxo 27 (n acetylhydroxylamino) 6,11,17,22 tetraazaheptaeicosane, B Deferoxamine, B Desferrioxamine, Butanediamide N' (5 ((4 ((5 (acetylhydroxyamino)pentyl)amino) 1,4 dioxobutyl)hydroxyamino)pentyl) N (5 aminopentyl) N hydroxy, Deferoxamine, Deferoxamine (product), Deferoxamine (substance), Deferoxamine B, DEFEROXAMINE PREPARATION, Deferoximine, Deferrioxamine, Deferrioxamine B, Desferioximine, desferrioxamine, Desferrioxamine B, Desferroxamine, DFO Desferrioxamine, N' (5 ((4 ((5 (Acetylhydroxyamino)pentyl)amino) 1,4 dioxobutyl)hydroxyamino)pentyl) N (5 aminopentyl) N hydroxybutanediamide, N (5 (3 (5 Aminopentyl)hydroxycarbamoyl)propionamido)pentyl) 3 ((5 (N hydroxyacetamido)pentyl)carbamoyl)propionohydroxamic Acid, Brand name/Desferal (Deferoxamine)

Treatment

Drug Dosage

DRUG/.$$$$ Very Expensive

DRUG/Injectable medication (parenteral)

DRUG/Intramuscular injection RX

DRUG/Orally ineffective drug

Definition

Chelator for iron intoxication/poisoning; parenteral preparation only

(Edit)

External Links Related to Deferoxamine (Desferal) Administration/Toxicity

PubMed (National Library of Medicine)

NGC (National Guideline Clearinghouse)

Medscape (eMedicine)

Harrison's Online (accessmedicine)

NEJM (The New England Journal of Medicine)

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