Disease Information for Dapsone (avlosulfone) Administration/Toxicity

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Clinical Manifestations
Signs & Symptoms
Red/erythema skin discoloration
Blue skin discoloration/Skin color
Erythroderma
Photosensitivity/Sunsensitive skin
Rash
Motor and sensory neuropathy/Polyneuropathy signs
Paresthesias
Cherry red spot/retinal sign
Demographics & Risk Factors
Established Disease Population
Patient/G6PD RBC hemolysis
Laboratory Tests
Abnormal Lab Findings - Increased
Methemoglobin (Lab)
URINE Methemoglobin
Associated Diseases & Rule outs
Associated Disease & Complications
Anemia
Anemia, hemolytic, toxic
DRESS/Drug Hypersensitivity Syndrome
Drug induced Hemolytic anemia.
Drug induced Neutropenia.
Drug induced Peripheral neuropathy.
Drug induced Photosensitivity rash
Drug rash/Drug induced rash
Erythema multiforme
Granulocytopenia/Neutropenia
Hemolysis anemia/acute/active
Methemoglobin inducing poisons/toxicity
Methemoglobinemia
Motor neuropathy
Peripheral neuropathy
Photosensitivity dermatitis
Phototoxicity
Polyneuritis
Sulfones effect/toxicity
Toxic peripheral/polyneuropathy
Polyneuropathy
Disease Synergy - Causes
Synergy/G6PD deficiency
Disease Mechanism & Classification
Drugs
DRUG/Antibiotic/antibacterial drug (example)
DRUG/Antibiotic/Antimicrobial drugs (category)
DRUG/Anti-leprosy antibiotic (example)
DRUG/Antimalarial medications (examples)
DRUG/Enterohepatic recirculation/elimination
DRUG/Sulfa drug/antibiotic/congeners (example)
DRUG/Sulfone antibiotic (example)
Pathophysiology
Pathophysiology/Hemolytic process/effect
Process
PROCESS/Medication/Drug (CONFIRM dose/before treatment)
Toxin
TOXIN/Enterohepatic recirculation/Use more charcoal
Synonyms
Synonym
4,4' Diaminophenyl Sulfone, 4,4' Sulfonylbis(benzenamine), 4,4' Sulfonylbisbenzamine, 4,4' Sulfonylbisbenzeneamine, 4,4' Sulfonyldianiline, Bis(4 aminophenyl) sulfone, Bis(4 aminophenyl)sulfone, Croysulfone, DADPS, DAPSONE, Dapsone (product), Dapsone (substance), DAPSONE PREPARATION, DDS, Diaminodiphenylsulfone, Diaminodiphenylsulphone, Diaphenylsulfone, Diphenasone, Dumitone, Novophone, Sulfona MAE, Sulfone 4,4' Diaminophenyl, Sulfonyldianiline, Sulphadione, Brand name/Aczone (Dapsone) topical, Brand name/Avlosulfon (Dapsone)
Treatment
Drug Therapy - Indication
RX/Methylene blue
Drug Dosage
DRUG/.1990 or before
DRUG/Dose 100 mgm (Unit/Pill/Capsule size)
DRUG/Dose 25 mgm (Unit/Pill/Capsule size)
DRUG/Dose once daily (RX)
DRUG/Given prophylactically
DRUG/Oral medication (ex)
Definition

Anti-leprosy antibiotic drug;and also Antituberculosis antibiotic drug;second line therapy often in combination;oral preparation;Sulfa drug congener as sufone drug; other specific indications for leprosy and other protozoa

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External Links Related to Dapsone (avlosulfone) Administration/Toxicity
Google
Wikipedia
Merck
Images
PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
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