Disease Information for Cysticercosis, cerebral

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Clinical Manifestations
Signs & Symptoms
Central Facial Paralysis
CNS symptoms/signs
Drowsiness/somnolence
Facial weakness/droop, unilateral
Focal neurologic deficit
Headache
Headache/worse in afternoon/evening
Kennedy sign (papilledema conta-optic atrophy)
Neurologic manifestations/signs
Neurological symptoms/signs
Seizures
Psychiatric manifestations/problems/difficulties
Constitutional symptoms
Pains Worse in the Evening
Clinical Presentation & Variations
Presentation/Recurrent Aseptic Meningitis
Disease Progression
Course/Chronic disorder
Course/Chronic only
Demographics & Risk Factors
Exposure Factors
Exposure/Pets
Exposure/Raw pork ingestion
Travel, Geographic & Climate Related Factors
Residence/travel/Haiti
Residence/travel/Mexico
Residence/travel/Texas
Laboratory Tests
Microbiology & Serology Findings
Microlab/Taenia Solium isolate/larva
Abnormal Lab Findings - Increased
CSF Eosinophiles
Diagnostic Test Results
Other Tests & Procedures
Lumbar puncture/Increased CSF pressure/LP test
Pathology
PATH/Brain Focal Degeneration/Lesion
PATH/Brain/Leptomeningeal Lesions
PATH/Gliosis/Brain/CNS
CT Scan
CT Scan/Head avascular lesion
CT Scan/Head Brain Abnormality
CT Scan/Head Brain Cyst
CT Scan/Head Brain lesion/mass single
CT Scan/Head Brain Multiple mass lesions
CT Scan/Head Calcified Basal ganglia
CT Scan/Head/calcified cystic lesions
CT Scan/Head/lesion ring enhancement
MRI/Head Brain Abnormal
MRI/Head Cystic lesion brain
MRI/Head Scan Abnormal
MRI/MRA Head abnormal
MRI/MRA/Head neck abnormal
X-RAY
Xray/Basal ganglia calcification/Skull
Xray/Calcifications intracranial/brain/Skull
Xray/Multiple intracranial calcifications/Head
Xray/Skull posterior fossa cyst/cystic
Angiography
Angios/Cerebral abnormal
Angios/Cerebral avascular lesion/mass
Associated Diseases & Rule outs
Rule Outs
Alzheimers disease
Brain abscess
Brain tumor
Cryptococcoma/CNS
Meningioma
Meningitis, chronic
Primary Brain Neoplasm
Associated Disease & Complications
Brain abscess
Central diabetes insipidus
Cerebral cyst
Cerebral hemorrhage
Convulsions (grand mal)
Cysticercosis, cerebral
Eosinophilic meningoencephalitis
Hallucinations
Hemiparesis
Hemiplegia
Hydrocephalus, chronic acquired
Intracranial Mass/Effect
Meningitis, chronic
Partial complex seizure
Stroke/Child
Intracranial Lesion
Mass in Brain
Recurrent Meningitis
Spastic Hemiplegia
Disease Mechanism & Classification
Specific Agent
AGENT/Cestode/tapeworm parasite (ex)
AGENT/Encysted larval pathophysiology
AGENT/Endemic disease (ex)
AGENT/Larval effects
AGENT/Man/secondary parasitic host/pattern
AGENT/Metazoan parasite/agent
AGENT/Migrating/invading larval forms
AGENT/Parasites (category)
AGENT/Zoonosis disease (ex)
Class
CLASS/Brain/CNS disorder (ex)
CLASS/Neurologic (category)
Pathophysiology
Pathophysiology/Metastasizing parasitic cyst/cancer-like
Pathophysiology/CNS mass lesion effect
Pathophysiology/CSF Pressure Increased
Process
PROCESS/Complicating disorder (ex)
PROCESS/Complicating/Specific process disorder (ex)
PROCESS/Cysts (ex)
PROCESS/INCIDENCE/Regional specific
PROCESS/Infection/agent specific (category)
Synonyms
Synonym
Brain Cysticercosis, brain cysticercosis (etiology), brain cysticercosis (manifestation), Central Nervous System Cysticercosis, Cerebral cysticercosis, Cerebral cysticercosis (disorder), cerebral cysticercosis (etiology), cerebral cysticercosis (manifestation), CNS CYSTICERCOSIS, Cysticercosis Brain, cysticercosis brain (etiology), cysticercosis brain (manifestation), Cysticercosis Central Nervous System, cysticercosis cerebral (etiology), cysticercosis cerebral (manifestation), CYSTICERCOSIS CNS, Cysticercosis of central nervous system, Cysticercosis of central nervous system (disorder), Cysticercosis of CNS, Neurocysticercoses, Neurocysticercosis, Synonym/Neurocysticercosis
Treatment
Drug Therapy - Contraindication
TX/Antihelmithic drugs Caution
Drug Therapy - Indication
RX/Albendazole (Albenza)
RX/Corticosteroid (Cortisone)
RX/Praziquantel (Biltricide)
RX/Prednisone (Deltasone)
Surgical Procedures or Treatments
SX/Surgery
SX/Surgical resection/removal/biopsy
Definition

Neurocysticercosis; History of exposure to Taenia solium in an endemic region; concomitant or past intestinal tapeworm infection; Seizures, headache, and other findings of a focal space-occupying central nervous system lesion; Subcutaneous or muscular nodules (5–10 mm); calcified lesions on x-rays of soft tissues; Calcified or uncalcified cysts by CT scan or MRI; positive serologic tests;Human cysticercosis is infection by the larval (cysticercus) stage of the tapeworm T solium ; Cysticerci complete their development within 2–4 months after larval entry and live for months to 20 years; Initially, a live larva grows within a thin-walled 10–20 mm cyst (the vesicular cyst) but remains minimally antigenic, causes little or no perilesional inflammation, and does not enhance with contrast media on neuroimaging; Attached to the inner wall of the cyst is an invaginated protoscolex with four suckers and a crown of hooks; When host immune response or chemotherapy causes gradual death of the cyst, marked inflammation and pericyst edema can occur, producing a ring-like or nodular area of enhancement with contrast media (the granulomatous or enhancing cyst); concurrent events include cyst enlargement, mechanical compression, increased intracranial pressure, cerebrospinal fluid changes, and sometimes a vasculitis that results in small cerebral infarcts; The immune response is intense in many patients, but some show a remarkable tolerance; Later, as the cyst degenerates over 2–7 years, it may become undetectable with imaging or be replaced by fibrosis with calcification that is detectable; Locations of cysts in order of frequency are the central nervous system (where cysts at different life cycle stages—live, transitional, dead—may be present at the same time), When symptomatic, the incubation period is highly variable (usually from 1 to 5 years); Manifestations are due to mass effect, inflammatory response, or obstruction of the brain foramina and ventricular systems; Neurologic findings are varied and nonspecific, in large part determined by the number and location of the cysts; Acute invasive stage (cysticercotic encephalitis): This rare event, occurring shortly after invasion, results from extensive acute spread of cysticerci to the brain parenchyma; Fever, headache, myalgia, marked eosinophilia, and coma may occur;

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External Links Related to Cysticercosis, cerebral
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PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
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