Disease Information for Cryopyrin-associated Periodic Syndrome (CAPS)

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Clinical Manifestations
Signs & Symptoms
Cold urticaria
Ice Cube test/Urticaria Abnormal
Rash
Excess Thirst in Children
Myalgias
Fatigability
Headache in children
Mental Deficiency Child
Joint Pains
Chills
Cyclic Periodic Recurrent Fevers
Fatigue
Fatigue Tiredness Exhaustion
Fever, intermittant/recurrent
Bloodshot eyes/Conjunctival injection
Eye Pains, Bilateral
Disease Progression
Course/Attacks Episodic Spells
Course/Periodic Episodic
Demographics & Risk Factors
Population Group
Population/Pediatrics population
Sex & Age Groups
Population/Children/all
Laboratory Tests
Abnormal Lab Findings - Increased
WBC
C-reactive protein (Lab)
Interleukin 1 (IL-1) levels (Lab)
Interleukin-6 IL-6 Serum (Lab)
Serum Amyloid A (SSA)
Associated Diseases & Rule outs
Associated Disease & Complications
Amyloidosis, systemic
Cryopyrin-associated Periodic Syndrome (CAPS)
Mental retardation
Deafness Acquired
Disease Mechanism & Classification
Pathophysiology
Pathophysiology/Autoinflammatory (non-immune)
Pathophysiology/Auto-Inflammatory Disorder
Pathophysiology/Excess Interleukin I (IL-1) produced
Pathophysiology/CIAS1/NLRP-3 Gene Mutation
Process
PROCESS/Autosomal dominant hereditary disease (ex).
PROCESS/Hereditofamilial (category)
PROCESS/INCIDENCE/Extremely rare disease
PROCESS/Miscellaneous-Incidental
PROCESS/Immune system disorder (ex)
Synonyms
Synonym
Synonym/Chronic Neurologic Cutaneous Articular Syndrome, Synonym/Muckles Wells Syndrome/FCAS (1q44), Synonym/Neonatal Onset Multisystem Inflammatory Disorder
Treatment
Drug Therapy - Indication
RX/Canakinumab (Llaris)
RX/Rilonacept IL-1 Blocker (Arcalyst)
Definition
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External Links Related to Cryopyrin-associated Periodic Syndrome (CAPS)
Google
Wikipedia
Merck
Images
PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
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