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Disease Information for Crush syndrome (muscle injury severe)

Clinical Manifestations
Signs & Symptoms: Swelling/Puffy
: Acute Limb ischemia; Capillary Refill Time/CRT Abnormal
: Anterior leg pain; Cyanotic extremity; Forearm Mass; Muscles swelling; Swelling one extremity/limb; Swollen Limb; Thigh/Leg Swelling Unilateral Severe
: Mucous membrane pallor
Disease Progression: Course/Acute; Course/Potentially lethal/untreated; Lethal Potential
Laboratory Tests
Abnormal Lab Findings (Non Measured): ALT (SGPT) over 120/2 1/2 X normal elevation (Lab); AST/SGOT above 1000 units/very high; Renal function abnormalities (Lab); SGOT over 120 elevation/ 2 1/2 X normal (Lab); Transaminase elevation (Lab); Very High CPK; Very High LDH
Abnormal Lab Findings - Decreased: Fibrinogen, plasma (Lab)
Abnormal Lab Findings - Increased: Aldolase, serum (Lab); ALT (SGPT) (Alanine transferase) (Lab); Aspartamine aminotransferase (SGOT, AST) (Lab); AST (SGOT) (aspartamine transferase) (Lab); CK-MM (Lab); CPK/CK/Creatine kinase/Creatine phosphokinase (Lab); C-reactive protein (Lab); Creatine, serum (Lab); Lactic Dehydrogenase (LDH LH) (Lab); Magnesium (Lab); Myoglobin; Phosphate Serum (Lab); Potassium, serum (Lab); Uric acid, serum (Lab)
: URINE 17-Hydroxycorticosteroids; URINE Creatine; URINE Lipids; URINE Myoglobin; URINE Urobilinogen
Associated Diseases & Rule outs
Rule Outs: Cellulitis; Thrombophlebitis, deep vein
Associated Disease & Complications: Abdominal Compartment Syndrome; Acidosis; Acute anuria/renal failure; Acute Renal Failure; Acute Tubular Necrosis; Anterior tibial compartment fasciitis/syndrome; Arterial Occlusion; Azotemia/Acute; Brady-arrhythmia; Crush injury/Muscle injury severe; Death Outcome; Hyperkalemia; Hypermagnesemia; Hyperphosphatemia; Hyperuricemia; Hypovolemia; Hypovolemic shock; Muscle Hematoma; Myoglobinemia; Myoglobinuria; Peripheral gangrene; Potassium administration/effect/toxicity; Reflex sympathetic dystrophy/Sudeck's atrophy; Rhabdomyolysis; Thrombophlebitis Arm/Deep Vein; Thrombophlebitis, deep vein
Disease Mechanism & Classification
Class: CLASS/Extremities/Digits/Hand feet disorder (category); CLASS/Muscle disorder (ex); CLASS/Muscle/tendon/extremities (category); CLASS/Striated muscle disorder (ex)
Pathophysiology: Pathophysiology/Third spacing fluid shift; Pathophysiology/Volume redistribution
: Pathophysiology/Tissue hypoxia/potential
: Pathophysiology/Secondary bacterial lesion infection
Process: PROCESS/Trauma (category)
Synonyms
Synonym: Bywaters, Bywaters' syndrome, Crush kidney, Crush Syndrome, Crush syndrome (disorder), Crush Syndromes, crushing injury syndrome, Ischaemic muscular necrosis syndrome, Ischemic muscular necrosis syndrome, Renal failure after crushing, Renal failure following crush syndrome, Renal failure following crushing, Renal failure following crushing injury, Syndrome Crush, syndrome crushing injury, Syndromes Crush, Synonym/Bywaters syndrome, Synonym/Ischemic muscular necrosis syndrome
Treatment
Drug Therapy - Contraindication: RX/Potassium
Drug Therapy - Indication: RX/Bicarbonate; RX/Fluid/electrolytes intravenous; RX/Forced diuresis; RX/Hydration/fluids/IV; RX/Hyperbaric oxygen therapy; RX/Mannitol (Osmotrol); RX/Saline intravenous; SX/Debridement
Surgical Procedures or Treatments: SX/Surgery
Other Treatments: TX/Intensive care management
Definition: Be the first to add a definition for Crush syndrome (muscle injury severe)
External Links Related to Crush syndrome (muscle injury severe): Google; Wikipedia; Merck; Images; PubMed (National Library of Medicine); NGC (National Guideline Clearinghouse); Medscape (eMedicine); Harrison's Online (accessmedicine); NEJM (The New England Journal of Medicine)

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