Disease Information for Cronkhite-Canada syndrome

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Clinical Manifestations
Signs & Symptoms
Baldness/Alopecia
Cutaneous manifestations
Dysplasia Toenails
Fingernails brittle/thinner/splitting
Hair loss
Increased pigmentation/tanning/hyperpigmented
Loss of body hair/thinning
Nails hypoplastic/dysplastic
Non-scarring Alopecia/balding
Abdominal Pain
Blood in stool
Diarrhea
Fatty food intolerance
Flatus/gas foul smelling
Foul stool
Gastric symptoms/signs
Glove stool exam guaiac positive
Hematochezia/Blood per Rectum
Rectal bleeding, gross red
Rectal Blood/Bleeding
Rectal Blood/Bleeding in Children
Stool Bulky/greasy/frothy/malodorous
Weight Loss
Women sicker than men
Clinical Presentation & Variations
Presentation/GI Bleeding Recurrent No obvious source
Disease Progression
Course/Chronic disorder
Course/Chronic only
Course/Lethal possible/not usual
Demographics & Risk Factors
Past History
Past History/GI Bleeding
Family History
Family history/GI Bleeding
Sex & Age Groups
Population/Sixties-adult
Laboratory Tests
Abnormal Lab Findings (Non Measured)
Microcytes/small RBCs on Blood smear
Microcytosis/microcytic anemia (Lab)
Fecal Globin Immunochemical Test positive
Abnormal Lab Findings - Decreased
Albumin, serum (Lab)
Hematocrit (Lab)
Hemoglobin (Lab)
MCV/Mean Corpuscular Volume (Lab)
RBC/Red Blood Count (Lab)
Abnormal Lab Findings - Increased
STOOL Fat Sudan stain
STOOL Occult blood
Diagnostic Test Results
Other Tests & Procedures
Colonoscopy/Abnormal
Colonoscopy/Multiple polyps
Colonoscopy/Polyp
Gastroscopy/Abnormal
Pathology
BX/Intestinal biopsy/Jejunal/Abnormal
BX/Polyp inflammatory cystic pattern
CT Scan
CT/Enterography Abnormal
X-RAY With contrast
BE/Abnormality (barium enema)
BE/Multiple colon polyps (Xray)
BE/Multiple filling defects of colon (Xray)
SBS/Abnormal Small Bowel Series
SBS/Multiple intraluminal defects (Xray)
SBS/Multiple nodules/intestinal (Xray)
UGI/Abnormal
UGI/Gastric multiple filling defects
Associated Diseases & Rule outs
Associated Disease & Complications
Alopecia areata
Anemia
Anemia of blood loss
Bacteria intestinal overgrowth syndrome
Cachexia/inanition/wasting
Colon polyp
Cronkhite-Canada syndrome
Disaccharidase deficiency
Electrolyte imbalance
Gastric adenoma (polyp)
Gastrointestinal bleeding
Hyperpigmentation
Hypoalbuminemia Hypoproteinemia
Intestinal polyp (small bowel)
Iron deficiency anemia
Malabsorption/Steatorrhea syndrome
Multiple colon polyps
Multiple gastric polyps
Nail dystrophy
Onycholysis
Protein losing enteropathy
Recurrent GI Bleeding
Lower GI bleeding
Recurrent GI bleed/elderly/no real source
Disease Mechanism & Classification
Class
CLASS/Intestinal/stomach/gut (category)
CLASS/Multisystem/organ involvement/pathology (ex)
Pathophysiology
Pathophysiology/Genomic indentifiers (polymorphism/snip/mutations)
Pathophysiology/Fat Malabsorption
Pathophysiology/Fat soluble Vitamin Malabsorption
Process
PROCESS/Benign tumor (ex).
PROCESS/Constitutional/essential disorder (ex)
PROCESS/Hamartoma type neoplasm (ex)
PROCESS/Hereditofamilial (category)
PROCESS/Hereditofamilial/tumor syndrome (ex)
PROCESS/INCIDENCE/Esoteric disease (example)
PROCESS/INCIDENCE/Rare disease (ex)
PROCESS/Neoplastic (category)
PROCESS/Polyps (ex)
PROCESS/Familial polyposis/colon (ex)
Synonyms
Synonym
Canada Cronkhite syndrome, CCS Cronkhite Canada syn, CCS Cronkhite Canada syndrome, Cronkhite Canada polyposis, Cronkhite Canada syndrome, Cronkhite Canada syndrome (disorder), Gastrointestinal multiple polyposis syndrome, POLYPOSIS SKIN PIGMENTATION ALOPECIA AND FINGERNAIL CHANGES, Synonym/Non-familial gastrointestinal polyp syndrome, Synonym/Polyposis/intestinal/ectodermal changes
Definition
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External Links Related to Cronkhite-Canada syndrome
Google
Wikipedia
Merck
Images
PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
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