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Disease Information for Cronkhite-Canada syndrome

Clinical Manifestations
Signs & Symptoms: Baldness/Alopecia; Cutaneous manifestations; Dysplasia Toenails; Fingernails brittle/thinner/splitting; Hair loss; Increased pigmentation/tanning/hyperpigmented; Loss of body hair/thinning; Nails hypoplastic/dysplastic; Non-scarring Alopecia/balding
: Abdominal Pain; Blood in stool; Diarrhea; Fatty food intolerance; Flatus/gas foul smelling; Foul stool; Gastric symptoms/signs; Glove stool exam guaiac positive; Hematochezia/Blood per Rectum; Rectal bleeding, gross red; Rectal Blood/Bleeding; Rectal Blood/Bleeding in Children; Stool Bulky/greasy/frothy/malodorous
: Weight Loss; Women sicker than men
Clinical Presentation & Variations: Presentation/GI Bleeding Recurrent No obvious source
Disease Progression: Course/Chronic disorder; Course/Chronic only; Course/Lethal possible/not usual
Demographics & Risk Factors
Past History: Past History/GI Bleeding
Family History: Family history/GI Bleeding
Sex & Age Groups: Population/Sixties-adult
Laboratory Tests
Abnormal Lab Findings (Non Measured): Microcytes/small RBCs on Blood smear; Microcytosis/microcytic anemia (Lab)
: Fecal Globin Immunochemical Test positive
Abnormal Lab Findings - Decreased: Albumin, serum (Lab); Hematocrit (Lab); Hemoglobin (Lab); MCV/Mean Corpuscular Volume (Lab); RBC/Red Blood Count (Lab)
Abnormal Lab Findings - Increased: STOOL Fat Sudan stain; STOOL Occult blood
Diagnostic Test Results
Other Tests & Procedures: Colonoscopy/Abnormal; Colonoscopy/Multiple polyps; Colonoscopy/Polyp; Gastroscopy/Abnormal
Pathology: BX/Intestinal biopsy/Jejunal/Abnormal; BX/Polyp inflammatory cystic pattern
CT Scan: CT/Enterography Abnormal
X-RAY With contrast: BE/Abnormality (barium enema); BE/Multiple colon polyps (Xray); BE/Multiple filling defects of colon (Xray); SBS/Abnormal Small Bowel Series; SBS/Multiple intraluminal defects (Xray); SBS/Multiple nodules/intestinal (Xray); UGI/Abnormal; UGI/Gastric multiple filling defects
Associated Diseases & Rule outs
Associated Disease & Complications: Alopecia areata; Anemia; Anemia of blood loss; Bacteria intestinal overgrowth syndrome; Cachexia/inanition/wasting; Colon polyp; Cronkhite-Canada syndrome; Disaccharidase deficiency; Electrolyte imbalance; Gastric adenoma (polyp); Gastrointestinal bleeding; Hyperpigmentation; Hypoalbuminemia Hypoproteinemia; Intestinal polyp (small bowel); Iron deficiency anemia; Malabsorption/Steatorrhea syndrome; Multiple colon polyps; Multiple gastric polyps; Nail dystrophy; Onycholysis; Protein losing enteropathy; Recurrent GI Bleeding
: Lower GI bleeding; Recurrent GI bleed/elderly/no real source
Disease Mechanism & Classification
Class: CLASS/Intestinal/stomach/gut (category)
: CLASS/Multisystem/organ involvement/pathology (ex)
Pathophysiology: Pathophysiology/Genomic indentifiers (polymorphism/snip/mutations)
: Pathophysiology/Fat Malabsorption; Pathophysiology/Fat soluble Vitamin Malabsorption
Process: PROCESS/Benign tumor (ex).; PROCESS/Constitutional/essential disorder (ex); PROCESS/Hamartoma type neoplasm (ex); PROCESS/Hereditofamilial (category); PROCESS/Hereditofamilial/tumor syndrome (ex); PROCESS/INCIDENCE/Esoteric disease (example); PROCESS/INCIDENCE/Rare disease (ex); PROCESS/Neoplastic (category); PROCESS/Polyps (ex)
: PROCESS/Familial polyposis/colon (ex)
Synonyms
Synonym: Canada Cronkhite syndrome, CCS Cronkhite Canada syn, CCS Cronkhite Canada syndrome, Cronkhite Canada polyposis, Cronkhite Canada syndrome, Cronkhite Canada syndrome (disorder), Gastrointestinal multiple polyposis syndrome, POLYPOSIS SKIN PIGMENTATION ALOPECIA AND FINGERNAIL CHANGES, Synonym/Non-familial gastrointestinal polyp syndrome, Synonym/Polyposis/intestinal/ectodermal changes
Definition: Be the first to add a definition for Cronkhite-Canada syndrome
External Links Related to Cronkhite-Canada syndrome: Google; Wikipedia; Merck; Images; PubMed (National Library of Medicine); NGC (National Guideline Clearinghouse); Medscape (eMedicine); Harrison's Online (accessmedicine); NEJM (The New England Journal of Medicine)

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