Disease Information for Costochondritis (Tietze) Syndrome

Clinical Manifestations
Signs & Symptoms
Breast Pain
Breast pain/soreness/Mastalgia
Acute Chest Pain
Acute Chest Pain in Children
Acute Chest Pain in Elderly
Chest Pain
Chest pain effected by position (central)
Chest Pain in Children
Chest Pain Sharply Localized
Chest pain, substernal/midline
Non-Pleuritic Chest Pain
Chest pain exacerbated on deep breathing
Chest pain/non-cardiac
Chest pains/recurrent/chronic
Chest Wall Pain
Chest wall tenderness
Costochondral tenderness
Costochondral/area inflammatory signs
Inspiratory central chest pain
Left anterior chest pain
Painful cough
Pleuritic chest pain
Rib tenderness
Enlarged costochondral joints/ribs
Sternal tenderness
Disease Progression
Course/Benign course/disorder
Course/Self limited usually
Demographics & Risk Factors
Ethnic or Racial Factors
Recent Event
Recent/Severe Stress Situation
Established Disease Population
Patient/Tension Headaches often
Patient/Anxious/chronic anxiety neurosis
Patient/Stress situation/anxious
Population Group
Young Adult
Sex & Age Groups
Population/Adult ('twenties')
Population/Adult Aged Only
Population/Man patient
Population/Young adult
Laboratory Tests
Abnormal Lab Findings (Non Measured)
Normal CBC (complete blood count) (Lab)
Diagnostic Test Results
Isotope Scan
Isotope/Cardiac Stress Thallium/Sestimibi scan/Normal
EKG/Normal (ECG)
Xray/Normal chest film
Associated Diseases & Rule outs
Rule Outs
Angina pectoris
Costochondritis/chest-wall pain syndrome
Mitral valve prolapse syndrome
Myocardial infarction, acute
Pulmonary embolism
Associated Disease & Complications
Costochondritis/chest-wall pain syndrome
Disease Mechanism & Classification
CLASS/Cartilage involvement/disorder (ex)
CLASS/Rib involvement/disorder (ex)
CLASS/Skeletal (category)
Pathophysiology/Myocardial Ischemia Non-Arteriosclerosis
PROCESS/Inflammatory/Traumatic/regeneration (ex)
Chondritides, Costal, chondritis costal, chondritis costal, Tietze, Chondritis, Costal, chondrocostal junction syndrome, Chondrocostal junction syndrome (Tietze), CHONDROPATHIA TUBEROSA, chostochondritis, Costal Chondritides, COSTAL CHONDRITIS, costal chondritis, Tietze, Costalchondritis, Costalchondritis (disorder), Costochondral junction syndrom, Costochondral junction syndrome, costochondritis, Costochondritis (disorder), Costochrondritis, Cyriax's syndrome, overlap syndrome chondrocostal (Tietze), Peristernal perichondritis, Slipping rib syndrome, syndrome chondrocostal junction, syndrome costochondral junction, Syndrome, Tietze's, Tietze, Tietze Syndrome, Tietze's disease, Tietze's disease (disorder), Tietzes syndrome, TIETZE'S SYNDROME, Synonym/Benign chest wall pain Syndrome, Synonym/Chest Wall pain syndrome, Synonym/Chondrodynia costosternalis, Synonym/Chondropathia tuberosa, Synonym/Costochondral junction syndrome, Synonym/Costosternal syndrome, Synonym/Peristernal perichondritis, Synonym/Tietze's syndrome
Drug Therapy - Indication
RX/Non-steroidal anti-inflammatory drugs
Drug Dosage
RX/Lidocaine patch indication
TX/Reassurance (self-limited/non-progressive)
Other Treatments
TX/Exercises/physical therapy

Costochondritis AKA Tietze Syndrome; Chondropathia Tuberosa; Costochondral Junction Syndrome; Costosternal Chondrodynia; Chest wall pain syndrome; Tietze syndrome is a rare, inflammatory disorder characterized by chest pain and swelling of the cartilage of one or more of the upper ribs (costochondral junction); Onset of pain may be gradual or sudden and may spread to affect the arms and/or shoulders; Tietze syndrome is considered a benign syndrome and, in some cases, may resolve itself without treatment; The exact cause of Tietze syndrome is not known------[NORD website 2005]----------

Costochondritis is a common form of inflammation of the cartilage where ribs attach to the breast bone, the sternum; The inflammation can involve multiple cartilage areas on both sides of the sternum but usually is on one side only (left) ; The cause(s) of costochondritis is(are) not known and may involve several factors; Possible causes include heredity (genetic predisposition), viruses, and trauma (injury); Costochondritis can be an independent condition by itself or sometimes be a feature of a more widespread disorder; Examples of illnesses that can feature costochondritis include fibromyalgia, psoriatic arthritis, ankylosing spondylitis, reactive arthritis, and inflammatory bowel disease (such as ulcerative colitis and Crohn"s disease );Costochondritis should be distinguished from Tietze syndrome, a condition involving the same area of the front of the chest; Costochondritis is not associated with swelling, as opposed to Tietze syndrome where swelling is characteristic; Tietze syndrome is an inflammation of the costochondral cartilages of the upper front of the chest; Patients with Tietze syndrome develop tenderness and swelling over the ribs and cartilage near the breast bone (sternum); Redness, tenderness, and heat can also be present but a localized swelling is the distinguishing finding;


External Links Related to Costochondritis (Tietze) Syndrome
PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)