Disease Information for Codeine Administration/Toxicity

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Clinical Manifestations
Signs & Symptoms
Slow pulse/Bradycardia
Pruritis Itching
Constipation Children
Constipation in Elderly
Nausea
Vomiting
Vomiting in Children
Staggering Gait
Unable to tandem walk/straight line
Unconscious/Narcosis status
Bradypnea Decreased respiratory rate
Laboratory Tests
Abnormal Lab Findings - Increased
Lipase (Lab)
Associated Diseases & Rule outs
Associated Disease & Complications
Coma/Unconscious
Constipation
Erythema multiforme
Obstipation
Opiate/Morphine overdose toxidrome
Urticaria/hives
Ataxia Disorder
Disease Synergy - Causes
Triggers of mastocytosis crises/abdominal pain
Disease Mechanism & Classification
Drugs
DRUG/Anti-Ptussive/Cough
DRUG/Dangerous for kids (10Kg)/Very
DRUG/Important Acute care drugs (example)
DRUG/Mast cell lysis/drug effect
DRUG/Narcotic/analgesic drug (category)
DRUG/Narcotic/Opiate-opioid medication (example)
DRUG/Opioid codeine-like agonist drug (example)
DRUG/P450 metabolic pathway/competitor
DRUG/Safe in pregnancy patient (B)
Pathophysiology
Pathophysiology/Tissue hypoxia/potential
Process
PROCESS/Medication/Drug (CONFIRM dose/before treatment)
Toxin
TOXIN/Decreases Respiratory Rate
Synonyms
Synonym
CODEINE, Codeine (product), Codeine (substance), CODEINE PREPARATION, Methyl morphine, Methylmorphine, Morphinan 6 ol, 7,8 didehydro 4,5 epoxy 3 methoxy 17 methyl , (5alpha,6alpha), N Methylmorphine, Brand name/Ambenyl (Bromodiphenhydramine-Codeine), Brand name/Empirin/Codeine (Codeine-Aspirin-Caffeine), Brand name/Triacin-C (Comb), Brand name/Tylenol Codeine combination
Treatment
Drug Dosage
DRUG/Dose PRN (as needed)
Definition

Opiate narcotic analgesic drugs; oral preparations; nausea and respiratory depression and constipation problems occur; some addicting potential; injection causes hives

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External Links Related to Codeine Administration/Toxicity
Google
Wikipedia
Merck
Images
PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
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