Disease Information for Clofarabine (Clolar) Administration/Toxicity

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Associated Diseases & Rule outs
Associated Disease & Complications
Drug induced Myelosuppression.
Drug induced Neutropenia.
Disease Mechanism & Classification
Drugs
DRUG/ABVD ChemoRX protocol (comb)
DRUG/Active metabolites
DRUG/Anti-tumor antimetabolite (example)
DRUG/Breast milk secretion/Danger
DRUG/Chemotherapeutics/cancer drugs/etc (category)
DRUG/Cytotoxic/chemotherapy medication (example)
Synonyms
Synonym
Clofarabine (Clolar) Administration, Brand name/Clolar (Clofarabine )
Treatment
Drug Dosage
DRUG/2005 New Release
DRUG/Intravenous administraton RX
DRUG/Intravenous only RX
Definition

Chemotherapy cancer drug; Anti-neoplastic intravenous drug with active metabolites; purine nucleoside anti-metabolite that inhibits DNA synthesis by inhibition of ribonucleotide reductase and active at mitochondral membrane level; used for failed Acute lymphoblastic leukemia chemotherapy; intravenous preparation only; prodiuct of bone marrow and liver toxicity; Genzyme FDA release 2006

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External Links Related to Clofarabine (Clolar) Administration/Toxicity
Google
Wikipedia
Merck
Images
PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
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