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Disease Information for Thrombotic thrombocytopenic purpura (Clinical Manifestations)

Synonyms:

Disease Moschkowitz, microangiopathy thrombotic, Moschcowitz, MOSCHCOWITZ SYNDROME, Moschcowitz's syndrome, MOSCHKOWITZ DIS, Moschkowitz Disease, Moschowitz's syndrome, purpura thrombocytopenic thrombotic, PURPURA THROMBOHEMOLYTIC, Purpura thrombopaenic thrombotic, Purpura thrombopenic thrombotic, purpura thrombotic thrombocytopenic, Purpura Thrombotic Thrombopenic, T T P syndrome, thrombocytopenic purpura thrombotic, Thrombopenic Purpura Thrombotic, Thrombot thrombocytopen purpur, Thrombotic microangiopathy, Thrombotic microangiopathy (disorder), thrombotic thrombocytopenic purpura, Thrombotic thrombocytopenic purpura (disorder), Thrombotic Thrombopenic Purpura, TTP, TTP Thromb thrombocytop purp, TTP Thrombotic thrombocytopenic purpura

A disease characterized by thrombocytopenia, hemolytic anemia, bizarre neurological manifestations, azotemia, fever, and thromboses in terminal arterioles and capillaries<br>

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thrombotic thrombocytopenia purpura; Synonyms of Thrombotic Thrombocytopenic Purpura; One cause of Microangiopathic Hemolytic Anemia <br>

Moschowitz Disease; TTP; Thrombotic thrombocytopenia purpura (TTP) is a rare, serious blood disease; Major symptoms may include a severe decrease in the number of blood platelets (thrombocytopenia), abnormal destruction of red blood cells (hemolytic anemia), and disturbances in the nervous system; Kidney dysfunction and fever are also common; The exact cause of thrombotic thrombocytopenic purpura is unknown <br>

----------------------------------[Nord website 2006]-------<br>

Thrombocytopenic Purpura Thrombotic thrombocytopenic purpura (TTP) is a life-threatening multisystem disorder that is considered a true medical emergency; Moschcowitz first described TTP in 1924 when he noted that his 16 year-old patient had anemia; petechiae; microscopic hematuria; and at autopsy, disseminated microvascular thrombi; Since that time, the pathophysiology, etiology, and medical management of TTP has expanded; This life-threatening condition may have positive outcomes if recognized early and if medical intervention is initiated early;<br>

Thrombotic Thrombocytopenic Purpura is a syndrome characterized by microangiopathic hemolytic anemia, thrombocytopenia, neurologic abnormalities, fever, and renal dysfunction; With the introduction of plasma exchange, the survival rate has improved from approximately 3% prior to the 1960s to 82%

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