Disease Information for Smallpox (variola): Clinical Manifestations

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Signs & Symptoms
Hospital staff/secondary cases
Household/secondary cases
Paroxysmal Shivering
Rigors/Shaking chills
Teeth Chattering
Uncontrollable Shaking
Facial Malar flush/rash
Red/erythema skin discoloration
Blebs/vesicles/skin
Centripetal rash/extremities first
Coalescence skin lesions
Crusting Rash
Encrusting Skin Lesions
Erythroderma
Face skin lesions
Facial erythema
Facial rash
Fever and Rash
Multiple pox/pustule lesions
Painful/tender rash
Papular Rash
Papulosquamous Lesion
Papulosquamous rash
Pox rash/All same age eruption
Rash
Rash face/exposed areas/arms/neck
Rash hand/foot areas
Rash on palms and soles
Rash/Characteristic pattern/distribution
Sores/weeping sores skin/extremity
Vesicobullous rashes
Vesicular rash
Buccal ulcers
Tongue Ulcer
Lymphadenopathy Systemic
Muscle Pain
Myalgias
Tender or painful muscles/Myalgias
Apathy/Indifference
Headache
Headache, severe
Acutely ill patient/signs
Chills
Collapse/Prostration
Constitutional symptoms
Fever
Fever clears then rash
Fever Febrile Possible
Fever in Immigrants
Fever, high
Flu-Like Syndrome
High body temperature
Listlessness/lassitude
Malaise
Toxic and Febrile Septic
Photophobia/Light sensitive
Clinical Presentation & Variations
Presentation/Fever Immigrant Recent Home country visit
Presentation/Fever recent Travel Long visit return
Presentation/Infection Complication Cardiac Severe
Presentation/ Papular Rash Face Upper Arms
Presentation/Pox rash Face Hands Feet Fever Prostration
Disease Progression
Course/Acute
Course/Acute only
Course/Illness not recurrent
Course/Lethal
Course/Potentially lethal/untreated
Course/Prodrome
Incubation/Intermediate
Lethal Potential
Onset/Abrupt/Sudden
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