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Disease Information for Smallpox (variola): Clinical Manifestations

Signs & Symptoms: Hospital staff/secondary cases; Household/secondary cases; Paroxysmal Shivering; Rigors/Shaking chills; Teeth Chattering; Uncontrollable Shaking
: Facial Malar flush/rash
: Red/erythema skin discoloration
: Blebs/vesicles/skin; Centripetal rash/extremities first; Coalescence skin lesions; Crusting Rash; Encrusting Skin Lesions; Erythroderma; Face skin lesions; Facial erythema; Facial rash; Fever and Rash; Multiple pox/pustule lesions; Painful/tender rash; Papular Rash; Papulosquamous Lesion; Papulosquamous rash; Pox rash/All same age eruption; Rash; Rash face/exposed areas/arms/neck; Rash hand/foot areas; Rash on palms and soles; Rash/Characteristic pattern/distribution; Sores/weeping sores skin/extremity; Vesicobullous rashes; Vesicular rash
: Buccal ulcers; Tongue Ulcer
: Lymphadenopathy Systemic
: Muscle Pain; Myalgias; Tender or painful muscles/Myalgias
: Apathy/Indifference; Headache; Headache, severe
: Acutely ill patient/signs; Chills; Collapse/Prostration; Constitutional symptoms; Fever; Fever clears then rash; Fever Febrile Possible; Fever in Immigrants; Fever, high; Flu-Like Syndrome; High body temperature; Listlessness/lassitude; Malaise; Toxic and Febrile Septic
: Photophobia/Light sensitive
Clinical Presentation & Variations: Presentation/Fever Immigrant Recent Home country visit; Presentation/Fever recent Travel Long visit return
: Presentation/Infection Complication Cardiac Severe
: Presentation/ Papular Rash Face Upper Arms; Presentation/Pox rash Face Hands Feet Fever Prostration
Disease Progression: Course/Acute; Course/Acute only; Course/Illness not recurrent; Course/Lethal; Course/Potentially lethal/untreated; Course/Prodrome; Incubation/Intermediate; Lethal Potential; Onset/Abrupt/Sudden

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