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Disease Information for Progressive Supranuclear Palsy: Clinical Manifestations

Signs & Symptoms: Akinetic rigid frozen Posture; Vertical Diplopia
: Facial muscle rigidity; Frontalis Overactivity; Mask-like facies; Staring Expression
: Choking; Dysphagia Liquids; Dysphagia Swallowing Difficulties; Gagging; Regurgitation; Slow eating pattern; Unable to swallow
: Drooling; Pharyngeal cordination problems
: Muscle stiffness/rigidity; Retrocollis
: Apathy/Indifference; Ataxia; Axial dystonia; Axial dystonia, progressive; Basal ganglion signs; Bradykinesia; Cognitive defect; Cognitive defects/multiple types; Cranial nerve abnormalities/involvement/signs; Difficulty concentrating/Distraction/Forgetful; Dysarthria; Dysconjugate gaze; Dystonia; Dystonia, acquired; Extrapyramidal signs; Facial weakness/droop, unilateral; Jaw jerk increased; Myoclonus/Myoclonic jerks on exam; Nasal speech/regurgitation; Near recall/memory deficit/defect; Nuchal dystonia; Odd body posturing; Passive stretch resistance increased; Postural lability/easy to push over; Rapidly progressive dementia; Retropulsion/propulsion gait; Slow speech; Speech Locution Problems; Staggering Gait; Unable to tandem walk/straight line; Vertical nystagmus
: Depressed/discouraged/sad; Emotional Incontinence/Lability; Emotional/affective lability; Loss inhibition/Dysinhibition, social; Volatility/wild mood swings
: Wry neck spasm
: Difficulty speaking/phonating; Difficulty Talking; Frequent Gagging Choking Clearing throat; Garbled/nasal sounding voice; Nasal/Hyponasal sound to voice; Voice change/disturbance/Unusual
: Falling
: Difficulty Focusing Eyes; Diplopia Double vision; Double Image Vision Confirmed; Eye symptoms/signs; Infrequent blinking/Stellwag sign; Squint/sign; Upward gaze paralysis/sign; Upward gaze paralysis/voluntary; Vertical gaze problems; Visual symptoms; Weak lateral gaze
Disease Progression: Course/5-year progressive; Course/Chronic disorder; Course/Chronic only; Course/Progressive/slowly chronic illness; Parkinsonism plus Other CNS issues

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