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Disease Information for Polyarteritis nodosa (Clinical Manifestations)
Classical polyarteritis nodosa, disease Kussmaul, KUSSMAUL DISEASE, Kussmaul's disease, PAN Polyarteritis nodosa, Panarteritis nodosa, periarteritis nodosa, Periarteritis nodosa systemic, POLYARTERITIS NODOSA, Polyarteritis nodosa (disorder), POLYARTERITIS NODOSA SYSTEMIC, Polyarteritis nodosum, Systemic periarteritis nodosa
A form of necrotizing vasculitis involving small- and medium-sized arteries; The signs and symptoms result from infarction and scarring of the affected organ system;<br>
commonly caused by chronic hepatitis B; steroid/lamivudin/plasma exchange for viral cause but cyclophosphamide for steroid resistant cases; viral replication increases with just steroid in hep b caes causes eariler cirrhosis; PAN involves skin,kidney,nerves and GI tract preferentially; this is a necrotic vasculitis<br>
causing renal failure and hypertension
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External Links Related to Polyarteritis nodosa
- Wikipedia
- Merck Manual
- PubMed
- National Guideline Clearinghouse
- eMedicine (medscape)
- Harrison's Online
- NEJM (The New England Journal of Medicine)
Clinical Manifestations
- Signs & Symptoms
- Bilateral ankle swelling
- Bilateral leg edema/swelling
- Decreased peripheral pulses
- High blood pressure/sign
- Osler's nodules/finger-tips/Osler's nodes
- Red/erythema skin discoloration
- Tachycardia/Fast heart rate
- Bruising/Ecchymosis
- Cutaneous granulomatous ulceration/signs
- Cutaneous manifestations
- Cutaneous ulcer/Skin ulcer
- Diascopy/vascular no blanching (skin)
- Erythematous generalized rash
- Fever and Rash
- Local Rubor/Redness
- Nodosal lesions
- Nodular rash
- Nodular rash with ulcer/necrosis/scarring effect
- Nodule/subcutaneous break down drain liquid
- Non-pruritic rash
- Painful subcutaneous nodules
- Papular Rash
- Petechiae in small clusters
- Petechiae, distal
- Petechiae/Petechial rash
- Petechial hemorrhages/subcutaneous
- Polymorphous rash
- Purpura
- Purpura, palpable
- Rash
- Rash, erythematous/Sunburn-like
- Skin nodules/Subcutaneous nodules
- Skin Ulcer with Eschar
- Subcutaneous nodules
- Subcutaneous Nodules in Elderly
- Tender nodules
- Ulcerations/skin
- Excessive/easy bruising tendency
- Abdominal Pain
- Acute abdomen
- Diffuse Abdominal Pain
- Poorly Localized Abdominal Pain
- Rectal bleeding, gross red
- Rectal Blood/Bleeding
- Weight loss in Elderly
- Tongue lesion/sign
- Hepatomegaly
- Palpable Liver
- Diffuse Aches and Pains
- Edema of Lower Extremities
- Finger tips/painful/tender
- Multiple Digits Painful
- Muscle Pain
- Myalgias
- Painful/finger tips
- Tender or painful muscles/Myalgias
- Weak/Weak as a kitten (symptom)
- Altered mental status Mental status change
- Confusion/agitation on exam
- Confusion/Disoriented
- Dizziness/Dizzy
- Headache
- Lethargy/torpor
- Motor and sensory neuropathy/Polyneuropathy signs
- Paresthesias
- Seizures
- Stroke Syndrome Child
- Stroke syndrome/signs
- Sudden unconsciousness
- Vertigo
- Bronchospasm signs
- Wheezing
- Arthralgias Polyarthralgias
- Arthritis and weight loss
- Arthritis in Children
- Arthritis with Abdominal Pain
- Arthritis with rash/dermatitis
- Joint Pains
- Joint pains Arthralgias in Elderly
- Hematuria
- Splenomegaly
- Chills
- Enervated/extreme acute fatigue
- Fever
- Fever Febrile Possible
- Fever of unknown origin/chronic fever
- Fever one week/non-infectious
- Fever Remittant/Recurrent
- Fever, intermittant/recurrent
- Flu-Like Syndrome
- High body temperature
- Localized Edema Swelling
- Localized pain
- Malaise
- Multiple organ/system failure patient
- Multisystem disease/signs
- Weakness
- Weakness non-neuromuscular/systemic
- Weight loss
- Eye symptoms/signs
- Typical Clinical Presentation
- Arthritis with Subcutaneous/Skin Nodules
- Clinical Presentation & Variations
- Disease Progression
- Course/Chronic disorder
- Course/Chronic only
- Course/Potentially lethal/untreated
- Lethal Potential
- Signs & Symptoms
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© 2009 MedTech USA, Inc. (last modified on 11/07/09)
