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Disease Information for Olfactory neuroblastoma (Clinical Manifestations)

Synonyms:

Accessory Sinus Esthesioneuroblastoma, Aesthesioneuroblastoma, Aesthesioneuroblastomas, Aesthesioneuroepithelioma, Asthesioneuroblastoma, Asthesioneuroblastoma (morphologic abnormality), Esthesioneuroblastoma, Esthesioneuroblastoma (morphologic abnormality), Esthesioneuroblastoma of Accessory Sinus, Esthesioneuroblastoma of Paranasal Sinus, Esthesioneuroblastoma of the Accessory Sinus, Esthesioneuroblastoma of the Paranasal Sinus, Esthesioneuroblastoma Olfactory, esthesioneuroblastoma paranasal sinus and nasal cavity, Esthesioneuroblastoma Paranasal Sinus Nasal Cavity, Esthesioneuroblastomas, Esthesioneuroblastomas Olfactory, esthesioneuroepithelioma, Esthesioneuroepithelioma (dup) (morphologic abnormality), Esthesioneuroepithelioma (morphologic abnormality), nasal cavity and paranasal sinus esthesioneuroblastoma, Nasal cavity esthesioneuroblastoma, Neuroblastoma Olfactory, Neuroblastomas Olfactory, Olfactory Esthesioneuroblastoma, Olfactory Esthesioneuroblastomas, Olfactory neuroblastoma, Olfactory neuroblastoma (disorder), Olfactory Neuroblastomas, Olfactory Neuroepithelioma, paranasal sinus and nasal cavity esthesioneuroblastoma, Paranasal sinus esthesioneuroblastoma, Paranasal Sinus Nasal Cavity Esthesioneuroblastoma, Paranasal Sinus Olfactory Neuroblastoma

A malignant olfactory neuroblastoma arising from the olfactory epithelium of the superior nasal cavity and cribriform plate. It is uncommon (3% of nasal tumors) and rarely is associated with the production of excess hormones (e.g., SIADH, Cushing Syndrome). It has a high propensity for multiple local recurrences and bony metastases. (From Holland et al., Cancer Medicine, 3rd ed, p1245; J Laryngol Otol 1998 Jul;112(7):628-33)

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