Disease Information for Mantle cell lymphoma/variant (Clinical Manifestations)

Centrocytic Small Cell Lymphoma, Centrocytic Small Cell Lymphomas, DIFFUSE LYMPHOCYTIC LYMPHOMA POORLY DIFFER, Diffuse Lymphocytic Lymphoma Poorly Differentiated, diffuse lymphoma lymphocytic poorly differentiated, diffuse PDL lymphoma, diffuse poorly differentiated lymphocytic lymphoma, DPDL lymphoma, LYMPHOCYTIC LYMPHOMA DIFFUSE POORLY DIFFER, Lymphocytic Lymphoma Diffuse Poorly Differentiated, Lymphocytic lymphoma poorly differentiated diffuse, Lymphocytic lymphosarcoma intermediate differentiation, Lymphocytic lymphosarcoma intermediate differentiation diffuse, Lymphoma Centrocytic Small Cell, lymphoma diffuse lymphocytic poorly differentiated, LYMPHOMA LYMPHOCYTIC DIFFUSE INTERMEDIATE DIFFER, Lymphoma Lymphocytic Diffuse Intermediate Differentiated, LYMPHOMA LYMPHOCYTIC DIFFUSE POORLY DIFFER, Lymphoma Lymphocytic Diffuse Poorly Differentiated, Lymphoma Mantle Cell, Lymphoma Mantle Zone, Lymphoma Small Cell Centrocytic, Lymphomas Centrocytic Small Cell, Lymphomas Mantle Cell, Lymphomas Mantle Zone, Malg lymph,lym,int difn,dif, Malign lymphoma,lymphocytic,intermediate differn diffuse, Malignant lymphoma centrocytic (obs), Malignant lymphoma lymphocytic intermediate differentiation diffuse, Malignant lymphoma lymphocytic intermediate differentiation diffuse (morphologic abnormality), Malignant lymphoma lymphocytic intermediate differentiation diffuse (obs), Malignant lymphoma lymphocytic poorly differentiated diffuse, Mantle Cell Lymphoma, Mantle cell lymphoma (morphologic abnormality), Mantle cell lymphomas, Mantle Zone Lymphoma, Mantle zone lymphoma (obs), Mantle Zone Lymphomas, MCL, Small Cell Lymphoma Centrocytic, Small Cell Lymphomas Centrocytic

Mantle cell lymphoma (MCL); A Non-Hodgkin"s lymphoma (NHLs) ; Mantle cell lymphoma (MCL) is a B-cell lymphoma that develops from malignant B-lymphocytes within a region of the lymph node known as the mantle zone; NHLs may also be categorized based upon certain characteristics of the cancer cells as seen under a microscope and how quickly they may tend to grow and spread; For example, NHLs may be characterized as "low-grade" (or indolent) lymphomas, which tend to grow slowly and result in few associated symptoms, or "intermediate-" or "high-grade" (aggressive) lymphomas, which typically grow rapidly, requiring prompt treatment; There is some debate concerning whether MCL should be categorized as a slow-growing (indolent) or rapidly-growing (aggressive) lymphoma; Although experts have classified MCL as an aggressive lymphoma, it has been shown to have certain characteristics of indolent lymphoma; According to various estimates, MCL represents approximately 2 to 7 percent of adult NHLs in the United States and Europe; It primarily affects men over the age of 50 years; Many affected individuals have widespread disease at diagnosis, with involved regions often including multiple lymph nodes, the spleen, and, potentially, the bone marrow, the liver, and/or regions of the digestive (gastrointestinal) tract; ---------------[NORD]--------------

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