Disease Information for Hepatic encephalopathy (Clinical Manifestations)

Synonyms:

coma hepaticum, ENCEPH HEPATIC, ENCEPH HEPATOCEREBRAL, ENCEPH PORTAL SYSTEMIC, ENCEPH PORTOSYSTEMIC, Encephalopathies Hepatic, Encephalopathies Hepatocerebral, Encephalopathies Portal Systemic, Encephalopathies Portosystemic, Encephalopathy hepatic, Encephalopathy hepatic, Encephalopathy Hepatocerebral, Encephalopathy Portal Systemic, Encephalopathy Portosystemic, Gaustad's syndrome, HE Hepatic encephalopathy, hepatic coma encephalopathy, HEPATIC ENCEPH, Hepatic Encephalopathies, HEPATIC ENCEPHALOPATHY, Hepatic encephalopathy (disorder), Hepatic encephalopathy syndrome, HEPATOCEREBRAL ENCEPH, Hepatocerebral Encephalopathies, Hepatocerebral Encephalopathy, Hepatocerebral encephalopathy RETIRED, hepatocerebral syndrome, portacaval encephalopathy, PORTAL SYSTEMIC ENCEPH, Portal Systemic Encephalopathies, Portal Systemic Encephalopathy, PORTOSYSTEMIC ENCEPH, Portosystemic Encephalopathies, Portosystemic encephalopathy, Transient hepatargy syndrome

A syndrome characterized by central nervous system dysfunction in association with LIVER FAILURE, including portal-systemic shunts. Clinical features include lethargy and CONFUSION (frequently progressing to COMA); asterixis; NYSTAGMUS; brisk oculovestibular reflexes; decorticate and decerebrate posturing; MUSCLE SPASTICITY; and bilateral extensor plantar reflexes (see REFLEX, BABINSKI). ELECTROENCEPHALOGRAPHY may demonstrate triphasic waves. (From Adams et al., Principles of Neurology, 6th ed, pp1117-20; Plum & Posner, Diagnosis of Stupor and Coma, 3rd ed, p222-5)

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Clinical Manifestations
- Signs & Symptoms
- Typical Clinical Presentation
  - Coma with normal Head CT Scan
- Disease Progression
  - Course/Eventual terminal event/death possible

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