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Disease Information for Cushing's disease/Syndrome: Clinical Manifestations

Signs & Symptoms: Particular physiognomy/Odd looking kids
: Bull neck/swelling; Craniofacial Abnormalities/Congenital; Facial edema/swelling; Facial Malar flush/rash; Facies particular; Fullness face/appearance; Head and neck swelling; Neck edema; Plethora/Red face/Ruddy look; Round face; Tight collar
: Breast Swelling Bilateral; Galactorrhea/Male; Lactorrhea in a male; Lactorrhea/Galactorrhea/Prolonged lactation
: Bilateral ankle swelling; Bilateral leg edema/swelling; Diastolic hypertension; High blood pressure child; High blood pressure/sign; Red/erythema skin discoloration; Tachycardia/Fast heart rate
: Acne flare; Acneiform eruption; Brown skin discoloration; Bruising/Ecchymosis; Comedones/pimples; Delayed/poor wound healing; Dewlap/Fatty tumor/suprasternal notch; Erythroderma; Facial erythema; Facial flushing/Beet red; Facial rash; Flushing; Hirsutism; Hypertrichosis; Increased pigmentation/tanning/hyperpigmented; Purpura; Skin fragile/thin/easily torn; Skin tears/easy abrasions signs; Striae/Purple striae; Supraclavicular Fat Pads Deposit; Thin skin/parchment-like skin
: Buffalo hump; Cushingoid habitus; Moon-like facies
: Anorgasmic male; Impotence, relative; Loss of libido,male; Sexual dysfunction
: Excessive/easy bruising tendency
: Excessive thirst/polydipsia; Increased abdominal girth/Potbelly; Poor weight gain/child; Weight gain in Children
: Decreased taste ability/Hypoguesia
: Truncal swelling/edema
: Renal Mass
: Bilateral arm edema; Edema of Lower Extremities; Loss of muscle mass; Muscle Atrophy; Muscle weakness; Proximal lower extremity weakness; Proximal muscle weakness; Thigh muscle atrophy; Thigh muscle weakness; Thin extremities; Weak/Weak as a kitten (symptom); Weakness climbing stairs
: Behavior problems; Delirium; Delirium/Agitated delirium; Excitement; Fatigability; Impaired judgement/signs; Insomnia; Irritability/short tempered; Loss of Taste; Weakness/Diffuse motor loss
: Amenorrhea; Amenorrhea, primary; Amenorrhea, secondary; Anorgasmia/Orgasm Dysfunction; Anorgasmic Female; Clitoral enlargement/newborn; Irregular periods/vaginal bleeding; Oligomenorrhea/Hypomenorrhea; Polymenorrhagia
: Destructive Behavior; Emotional outbursts/tantrums/Hot temper; Emotional/affective lability; Personality changes/gradual; Psychiatric manifestations/problems/difficulties; Psychotic behavior/symptomatic; Queer bizarre behavior/change; Volatility/wild mood swings
: Acute Back Pain; Back Pain; Backache; Chronic Back Pain
: Anosmia/Loss of sense of smell; Decreased sense of smell
: Diuresis/Large urine volumes; Kidney Mass; Polyuria; Polyuria and polydipsia
: Central obesity/sign; Chronic Fatigue; Enervated/extreme acute fatigue; Episodic symptoms/events; Fatigue; Fatigue Tiredness Exhaustion; Fatigue Tiredness in Elderly; Growth/development delay; Increase Waist/Hip Girth Ratio; Muscle Wasting/Diffuse; Short stature; Short stature Child; Spells/Episodes of weakness; Spousal/family concern/complaint; Thirst Increased; Truncal obesity; Weakness; Weakness non-neuromuscular/systemic; Weight gain
: Bilateral Eyelid Edema; Bloodshot eyes/Conjunctival injection; Periorbital edema/Puffy eyes; Red Eyes Bilateral; Scleral Injection
Clinical Presentation & Variations: Presentation/Multiple deformities newborn (odd look)
: Presentation/Hypertension Abrupt Onset
: Presentation/Sensitive to Diuretics Thiazide (Low K)
Disease Progression: Course/Circadian rhythm, same time event/flair
: Galactorrhea

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