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Disease Information for Cerebral gigantism of childhood (Sotos): Clinical Manifestations

Signs & Symptoms: Macrosomia; Particular physiognomy/Odd looking kids
: Broad forehead/facies; Craniofacial Abnormalities/Congenital; Facial Asymmetry; Facial hemihypertrophy; Facies particular; Pointed chin; Prominent chin; Prominent forehead/High forehead
: Fingernails brittle/thinner/splitting; Receding hairline; Thickened skin/diffuse
: Accelerated growth Child
: Increased body length/newborn; Large baby/birth weight increased
: Feeding/swallowing difficulties/infant
: High arched palate; Large tongue/macroglossia; Large/protruding jaw/prognathism; Precocious teeth eruption/child
: Hypotonia; Large hands/feet; Muscle weakness
: Awkward Uncoordinated Child; Clumsiness/poor coordination; CNS symptoms/signs; Delayed crawling milestone/infant; Delayed speech/language development; Delayed walking milestone/child; Development Motor Skills (Milestones) Delayed; Developmental milestones delayed; Hypereactive Child; Hypereactive/on exam; Infant Seizures; Infant/Head circumference increased; Limb ataxia/clumsiness child; Mental Deficiency Child; Nystagmus; Progressive macrocephaly/infant/sign; Seizures/Children/recurrent; Slow Motor Development
: Difficulty learning/school/workplace; Hyperactivity, child/signs; Impulsivity; Psychomotor retardation; Short attention span
: Arms too long for body; Asymmetric Limbs; Bossing forehead,infants; Macrocephaly/Large head; Megalocephaly; Skull/head enlargement; Skull/tall/dolichiocephalic deformity/sign; Tall child
: Delayed speech development/impediment; Snoring
: Accelerated growth rate child/below age five; Dysmorphic appearance/face; Lateral Asymmetry; Tall Adult; Weakness
: Downward sloping eyes/Antimongoloid slant
: True Vertigo Sign Confirmed
Clinical Presentation & Variations: Presentation/Multiple deformities newborn (odd look)
Disease Progression: Course/Chronic disorder; Course/Chronic only; Course/Prolonged/persistent/Not progressive

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