Disease Information for Acromegaly (Gigantism): Clinical Manifestations

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Signs & Symptoms
Macrosomia
Particular physiognomy/Odd looking kids
Swelling/Puffy
Craniofacial Abnormalities/Congenital
Enlarging nose
Facial edema/swelling
Facial/nose deformity/acquired
Facies particular
Heavy facial features
Leonine Facies/Jowles
Prominent forehead/High forehead
Prominent Nose
Prominent supraorbital ridges
Breast Discharge
Breast Swelling Bilateral
Galactorrhea/Male
Lactorrhea in a male
Lactorrhea/Galactorrhea/Prolonged lactation
Cardiomegaly/Heart dilatation
Clubbing
Clubbing of fingers/toes
High blood pressure/sign
Axillary sweating
Body odor increased/changed
Coarsening skin
Diaphoresis profuse/active sweating/acute
Excess loose skin/child
Excess Sweating Children
Hirsutism
Hyperhidrosis/Chronic sweating excess
Hypertrichosis
Increased pigmentation/tanning/hyperpigmented
Large Skin Pores
Oily Skin
Skin tags/papillomata/increased sudden new growth
Sweating Excess Perspiration
Thickened skin/diffuse
Accelerated growth Child
Acromegalic habitus
Delayed adolescence/secondary sex changes
Enlarged thyroid gland
Goiter/thyroid enlargement/mass
Male body habitus/female
Thyroid Mass
Thyromegaly/Symmetric enlargement
Virilism
Anorgasmic male
Impotence, relative
Large prostate
Loss of libido,male
Sexual dysfunction
Appetite increased
Increased spacing between teeth/sign
Large tongue/macroglossia
Large/protruding jaw/prognathism
Salivary Gland Enlargement
Swollen lips
Hepatosplenomegaly
Fleshy Hands
Hip Inner Thigh Pain
Large hands/feet
Muscle hypertrophy
Muscle weakness
Pain in Extremities/Melalgias
Proximal lower extremity weakness
Proximal upper extremity weakness
Soft, Doughy, Sweaty handshake
Swelling of hands and feet
Anesthetic hypesthetic limbs/areas
Bitemporal hemianopsia
Headache
Headache/chronic recurrent
Motor and sensory neuropathy/Polyneuropathy signs
Nerve trunk/enlarged, palpable
Paresthesias
Amenorrhea
Amenorrhea, secondary
Anorgasmia/Orgasm Dysfunction
Anorgasmic Female
Irregular periods/vaginal bleeding
Oligomenorrhea/Hypomenorrhea
Expiratory stridor or stertor
Increased libido
Arthralgias Polyarthralgias
Back Pain
Backache
Decreased Knee range of motion
Enlarged/deformed joints
Enlarging hands/feet/fingers
Foot arthritis, bilateral
Hip Pain
Increased Glove Size
Increased Shoe Size
Joint deformities
Joint effusion
Joint exam/signs
Joint Pains
Joint pains Arthralgias in Elderly
Joint Swelling
Knee Pain
Macrocephaly/Large head
Megalocephaly
Multiple Joint Arthritis
Single Joint Pain
Skeletal problems/symptoms/signs
Skull/head enlargement
Tall child
Wrist arthritis/signs
Wrist pain
Deepening of voice/Low voice
Hoarseness
Snoring
Voice change/disturbance/Unusual
Polyuria
Splenomegaly
Coarsened facial features
Decreased exercise tolerance/effort fatigue
Fatigue
Hypersomnia/Increased need for sleep
Increased Hat Size
Pallor
Poor Stamina
Tall Adult
Thirst Increased
Weakness
Weight gain
Peripheral vision/loss
Tunnel Vision
Vision Loss
Calcification/pinna cartilage/sign
Thick/Fleshy Earlobes
Clinical Presentation & Variations
Presentation/Multiple deformities newborn (odd look)
Presentation/Aggressive Osteoarthritis
Disease Progression
Course/Chronic disorder
Course/Chronic only
Onset/insidious
Galactorrhea
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