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Disease Information for Acromegaly (Gigantism): Clinical Manifestations

Signs & Symptoms: Macrosomia; Particular physiognomy/Odd looking kids; Swelling/Puffy
: Craniofacial Abnormalities/Congenital; Enlarging nose; Facial edema/swelling; Facial/nose deformity/acquired; Facies particular; Heavy facial features; Leonine Facies/Jowles; Prominent forehead/High forehead; Prominent Nose; Prominent supraorbital ridges
: Breast Discharge; Breast Swelling Bilateral; Galactorrhea/Male; Lactorrhea in a male; Lactorrhea/Galactorrhea/Prolonged lactation
: Cardiomegaly/Heart dilatation; Clubbing; Clubbing of fingers/toes; High blood pressure/sign
: Axillary sweating; Body odor increased/changed; Coarsening skin; Diaphoresis profuse/active sweating/acute; Excess loose skin/child; Excess Sweating Children; Hirsutism; Hyperhidrosis/Chronic sweating excess; Hypertrichosis; Increased pigmentation/tanning/hyperpigmented; Large Skin Pores; Oily Skin; Skin tags/papillomata/increased sudden new growth; Sweating Excess Perspiration; Thickened skin/diffuse
: Accelerated growth Child; Acromegalic habitus; Delayed adolescence/secondary sex changes; Enlarged thyroid gland; Goiter/thyroid enlargement/mass; Male body habitus/female; Thyroid Mass; Thyromegaly/Symmetric enlargement; Virilism
: Anorgasmic male; Impotence, relative; Large prostate; Loss of libido,male; Sexual dysfunction
: Appetite increased
: Increased spacing between teeth/sign; Large tongue/macroglossia; Large/protruding jaw/prognathism; Salivary Gland Enlargement; Swollen lips
: Hepatosplenomegaly
: Fleshy Hands; Hip Inner Thigh Pain; Large hands/feet; Muscle hypertrophy; Muscle weakness; Pain in Extremities/Melalgias; Proximal lower extremity weakness; Proximal upper extremity weakness; Soft, Doughy, Sweaty handshake; Swelling of hands and feet
: Anesthetic hypesthetic limbs/areas; Bitemporal hemianopsia; Headache; Headache/chronic recurrent; Motor and sensory neuropathy/Polyneuropathy signs; Nerve trunk/enlarged, palpable; Paresthesias
: Amenorrhea; Amenorrhea, secondary; Anorgasmia/Orgasm Dysfunction; Anorgasmic Female; Irregular periods/vaginal bleeding; Oligomenorrhea/Hypomenorrhea
: Expiratory stridor or stertor
: Increased libido
: Arthralgias Polyarthralgias; Back Pain; Backache; Decreased Knee range of motion; Enlarged/deformed joints; Enlarging hands/feet/fingers; Foot arthritis, bilateral; Hip Pain; Increased Glove Size; Increased Shoe Size; Joint deformities; Joint effusion; Joint exam/signs; Joint Pains; Joint pains Arthralgias in Elderly; Joint Swelling; Knee Pain; Macrocephaly/Large head; Megalocephaly; Multiple Joint Arthritis; Single Joint Pain; Skeletal problems/symptoms/signs; Skull/head enlargement; Tall child; Wrist arthritis/signs; Wrist pain
: Deepening of voice/Low voice; Hoarseness; Snoring; Voice change/disturbance/Unusual
: Polyuria
: Splenomegaly
: Coarsened facial features; Decreased exercise tolerance/effort fatigue; Fatigue; Hypersomnia/Increased need for sleep; Increased Hat Size; Pallor; Poor Stamina; Tall Adult; Thirst Increased; Weakness; Weight gain
: Peripheral vision/loss; Tunnel Vision; Vision Loss
: Calcification/pinna cartilage/sign; Thick/Fleshy Earlobes
Clinical Presentation & Variations: Presentation/Multiple deformities newborn (odd look)
: Presentation/Aggressive Osteoarthritis
Disease Progression: Course/Chronic disorder; Course/Chronic only; Onset/insidious
: Galactorrhea

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