Disease Information for Cladribine (Leustatin) Administration/Toxicity

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Laboratory Tests
Abnormal Lab Findings - Increased
Platelet count (Lab)
Associated Diseases & Rule outs
Associated Disease & Complications
Agranulocytosis
Bone marrow failure/exhaustion
Drug induced Myelosuppression.
Drug induced Nephritis/Nephropathy
Drug induced Peripheral neuropathy.
Drug induced Thrombocytopenia.
Granulocytopenia/Neutropenia
Myelitis, transverse
Myelosuppression
Nephritis, secondary
Peripheral neuropathy
Polyneuritis
Thrombocytopenia
Thrombocytosis
Toxic nephritis/Chronic persistent
Toxic Nephritis/Nephropathy
Toxic peripheral/polyneuropathy
Polyneuropathy
Disease Mechanism & Classification
Drugs
DRUG/Anti-neoplastic medications (examples)
DRUG/Anti-tumor antimetabolite (example)
DRUG/Breast milk secretion/Danger
DRUG/Chemotherapeutics/cancer drugs/etc (category)
DRUG/Impaired DNA metabolism effect/drug (example)
DRUG/Readily enters CNS/CSF Blood-brain barrier
DRUG/Specialized usage (example)
DRUG/Specific Hairy cell leukemia
DRUG/Teratogenic potential/effect (D plus )
Process
PROCESS/Medication/Drug (CONFIRM dose/before treatment)
Synonyms
Synonym
2 CdA, 2 Chloro 2 Deoxyadenosine, 2 Chloro 2' deoxyadenosine, 2 Chlorodeoxyadenosine, 2' Deoxy 2 chloroadenosine, 2CDA, Adenosine, 2 chloro 2' deoxy, CdA, chlorodeoxyadenosine, CHLORODEOXYADENOSINE 02, CHLORODEOXYADENOSINE 02 02, Cladribina, Cladribine, Cladribine (product), Cladribine (substance), CLADRIBINE PREPARATION, Cladribine product, Brand name/CdA (Cladribine), Brand name/Leustatin (Cladribine), Britain-BNF/Leustat (Cladribin), Synonym/Chlorodeoxyadenosine administration
Treatment
Drug Dosage
DRUG/1997 Approx. New Drug (RX)
DRUG/Dose 10 mgm/ml (Vial)
DRUG/Dose once daily (RX)
DRUG/Injectable medication (parenteral)
DRUG/Injectable preparation only
DRUG/Intravenous administraton RX
DRUG/Intravenous only RX
DRUG/Orphan/One indication drug (ex)
Definition

Cancer chemotherapy drug; Antimetabolite class usually substituted purine or pyrimidine bases interfere with DNA synthesis.

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External Links Related to Cladribine (Leustatin) Administration/Toxicity
Google
Wikipedia
Merck
Images
PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
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