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- Disease Information
- Disease Comparison
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Disease Processes ▼
- Auto Immune
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Major Organs-Systems ▼
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Disease Information for Cisplatin (Platinol) Administration/Toxicity
- Clinical Manifestations
- Signs & Symptoms
- Dizzy on Standing/Giddy Response
- Orthostatic drop in blood pressure
- Facial erythema
- Facial flushing/Beet red
- Flushing
- Flushing/upper body
- Bilateral Calf Pains
- Leg cramps,nocturnal
- Leg cramps/muscle spasm/pains
- Motor and sensory neuropathy/Polyneuropathy signs
- Papilledema on exam
- Paresthesias
- Acute Hearing Loss
- Sudden deafness
- Typical Clinical Presentation
- Presentation/Anaphylaxis with first dose/medication
- Laboratory Tests
- Abnormal Lab Findings - Decreased
- Magnesium (Lab)
- Abnormal Lab Findings - Increased
- Magnesium (Lab)
- Associated Diseases & Rule outs
- Associated Disease & Complications
- Anaphylactoid reaction/Non-IGE/Very first dose
- Anaphylaxis, generalized
- Angioedema/angioneurotic edema
- Ataxic neuropathy
- Deafness, sensorineural
- Drug Allergy
- Drug induced Hypomagnesemia
- Drug Induced Infusion Reaction
- Drug induced Neutropenia.
- Drug induced Peripheral neuropathy.
- Drug induced Renal failure,
- Fetal anomaly
- Granulocytopenia/Neutropenia
- Hemolytic-uremic syndrome
- Hypomagnesemia
- Magnesium deficiency
- Nephrogenic diabetes insipidus
- Orthostatic syncope Hypotension
- Pancreatitis, acute
- Peripheral neuropathy
- Polyneuritis
- Red Man Syndrome
- Toxic peripheral/polyneuropathy
- Polyneuropathy
- Deafness Acquired
- Disease Mechanism & Classification
- Drugs
- DRUG/Alkylating agents (example)
- DRUG/Chemotherapeutics/cancer drugs/etc (category)
- DRUG/CMV ChemoRX protocol (comb)
- DRUG/First dose caution
- DRUG/H-CAP protocol (four drugs) (comb)
- DRUG/M-VAC ChemoRx protocol (comb)
- DRUG/Platinum Chemotherapy agents
- DRUG/Teratogenic potential/effect (D plus )
- Process
- PROCESS/Medication/Drug (CONFIRM dose/before treatment)
- Toxin
- TOXIN/Causes Flushing/Redness
- Synonyms
- Synonym
- (SP 4 2) Diamminedichloroplatinum, CACP, CDDP, CDDP Cisplatin, cis DDP, cis Diaminedichloroplatinum, cis diammine dichloroplatinum, Cis diamminedichloridoplatinum, Cis diamminedichloro Platinum (II), cis Diamminedichloroplatinum, cis Diamminedichloroplatinum(II), Cis dichloroammine Platinum (II), cis dichlorodiammineplatinum, cis Dichlorodiammineplatinum(II), Cis platinous Diamine Dichloride, cis Platinum, cis platinum compound, Cis platinum II, Cis platinum II Diamine Dichloride, Cismaplat, Cisplatin, Cisplatin (product), Cisplatin (substance), CISPLATIN PREPARATION, Cisplatin product, Cisplatina, Cisplatinum, CPDD, Cysplatyna, DDP, Diaminedichloroplatinum, Diaminedichloroplatinum (substance), DIAMMINEDICHLOROPLATINUM CIS 02, Diamminodichloride, Platinum, Dichlorodiammineplatinum, DICHLORODIAMMINEPLATINUM CIS 02, PDD, Peyrone's Chloride, Peyrone's Salt, Platinoxan, platinum diamminodichloride, Platinum, Diaminedichloro , cis (8CI), Platinum, diamminedichloro , (SP 4 2), Brand name/CDDP (Cisplatin), Brand name/Platinol (Cisplatin), GEM-P Chemotherapy regimen
- Treatment
- Drug Dosage
- DRUG/Dose small test-dose method
- DRUG/Dose Unit dose Vial preparation
- Definition
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Platinum toxic effect drug. Primarily an Antineoplastic cancer chemotherapy drug. Alkylating agents interfere with methylation of DNA in mitosis, inhibits cell devision. Speciality use only is recommended; a dangerous class of drugs with predictable bone marrow suppression often.
(Edit)
- External Links Related to Cisplatin (Platinol) Administration/Toxicity
- Wikipedia
- Merck
- Images
- PubMed (National Library of Medicine)
- NGC (National Guideline Clearinghouse)
- Medscape (eMedicine)
- Harrison's Online (accessmedicine)
- NEJM (The New England Journal of Medicine)
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