Disease Information for Cisapride (Propulsid) Administration/Toxicity

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Diagnostic Test Results
EKG (ECG)
EKG/Drug induced QT prolongation (ECG)
Associated Diseases & Rule outs
Associated Disease & Complications
Cardiac arrhythmias
Cisapride effect
Drug induced Arrhythmias
Drug interaction often
Disease Mechanism & Classification
Drugs
DRUG/AcetylCholine release/gastrum
DRUG/Breast milk secretion/Danger
DRUG/Cholinergic agonist drug/effect (example)
DRUG/Cytochrome CY P450 3A4 degradation pathway
DRUG/Enteric/gut motor stimulation
DRUG/metabolized by CYP 3A pathway
DRUG/Metoclopramide-like Prokinetic activity
DRUG/Proarrhythmic drug effect (example)
Process
PROCESS/Medication/Drug (CONFIRM dose/before treatment)
Synonyms
Synonym
Cisapride (Propulsid) admin TOXIC, Brand name/Propulsid (Cisapride)TOXIC
Treatment
Drug Therapy - Contraindication
RX/Itraconazole (Sporonox)
RX/Ketoconazole (Nizoral)
Drug Dosage
DRUG/Dose 10 mgm (Unit/Pill/Capsule size)
DRUG/Dose QID Medication
DRUG/Drug discontinued/TOXIC (RX)
Definition

a gut motility drug; withdrawn because of arrhythmias/TOXIC

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External Links Related to Cisapride (Propulsid) Administration/Toxicity
Google
Wikipedia
Merck
Images
PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
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