Disease Information for Chronic Meningitis Syndrome

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Clinical Manifestations
Signs & Symptoms
Nausea
Vomiting
Vomiting recurrent
Confusion/Disoriented
Drowsiness/somnolence
Headache
Lethargy/torpor
Meningeal Signs
Neurologic manifestations/signs
Neurological symptoms/signs
Progressive headache
Stiff neck/Nuchal rigidity
Back Pain
Fever
Flu-Like Syndrome
High body temperature
Hypersomnia/Increased need for sleep
Prolonged prodrome febrile illness
Disease Progression
Course/Chronic disorder
Laboratory Tests
Microbiology & Serology Findings
Microlab/CSF Polymerase chain reaction/PCR abnormal
Abnormal Lab Findings (Non Measured)
Acute inflammatory markers elevated (Lab)
CSF abnormal
Abnormal Lab Findings - Increased
CSF Cells
CSF IGG synthesis rate
Diagnostic Test Results
Pathology
PATH/Brain/Leptomeningeal Lesions
Associated Diseases & Rule outs
Rule Outs
Cryptococcal meningitis
Subacute endocarditis, infective
Associated Disease & Complications
Drug induced Chronic Meningitis/inflammatory
Meningitis, chronic
Vomiting Excess/Chronic
Disease Mechanism & Classification
Class
CLASS/Meninges/pia/arachnoid involvement (ex)
CLASS/Neurologic (category)
Process
PROCESS/Infection/Abscess (ex)
Definition

chronic or indolent meningitis has a slow onset atypical presentation with more cognitive, psychotic, behavioral changes and pressure effects with headache, relentless often slow decline with torpor, slow decline or slow resolution; fungal, luetic,tuberculous, sarcoid, Behcets, lupus, angiitis syndromes are usual cause with or without HIV/AIDS; meningeal carcinomatosis/lymphoma metabolic and other encephalitides included---------------------

Ongoing (chronic) forms of meningitis occur when slow-growing organisms invade the membranes and fluid surrounding your brain; Although acute meningitis strikes suddenly, chronic meningitis develops over four weeks or more;Nevertheless, the signs and symptoms of chronic meningitis — headaches, fever, vomiting and mental cloudiness — are similar to those of acute meningitis;This type of meningitis is rare; TBC most common worldwide but after this Fungal meningitis usually than others in AIDS and chemotherapy and organ transplant or steroid dosing make patients at risk ; Fungal meningitis is relatively uncommon;Cryptococcal meningitis is a fungal form of the disease that affects people with immune deficiencies, such as AIDS;It"s life-threatening if not treated with an antifungal medication. Other causes: Meningitis can also result from noninfectious causes, such as drug allergies, some types of cancer and inflammatory diseases such as lupus.

---[cnn website health library 2006]-----------------------

Chronic meningitis is inflammation of the meninges that lasts a month or longer; Chronic meningitis affects people whose immune system is impaired because of AIDS, cancer, use of chemotherapy, or long-term use of the corticosteroid prednisone; However, tuberculosis, Lyme disease, or another infection can cause chronic meningitis in people whose immune system is functioning competently; The distinction between acute and chronic meningitis is not always clear, and sometimes the meningitis is described as subacute instead, especially inadequately treated bacterial meningitis;

Some infectious organisms invade the brain or the meninges and multiply slowly over weeks, months, or even years;Such organisms include Cryptococcus fungus (in people with an impaired immune system, such as those with AIDS) and the bacteria that cause tuberculosis, syphilis, or Lyme disease; Acute bacterial meningitis that has been partially treated but not eliminated by antibiotics may evolve into chronic meningitis; Some noninfectious disorders, such as sarcoidosis and some cancers (leukemia, lymphoma, brain tumors, and metastases to the brain), can invade and irritate the meninges, producing chronic meningitis; Chemotherapy drugs that are injected directly into the cerebrospinal fluid (such as methotrexate/RHEUMATREX

), drugs used in organ transplantation (such as cyclosporine/SANDIMMUNE/NEORAL and OKT3muromonab-CD3), and even nonsteroidal anti-inflammatory drugs (NSAIDs, such as ibuprofen/ADVIL,MOTRIN, NUPRIN.: Nonsteroidal Anti-Inflammatory Drugs can inflame the meninges, leading to chronic meningitis;

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External Links Related to Chronic Meningitis Syndrome
Google
Wikipedia
Merck
Images
PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
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