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- Disease Information
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Major Organs-Systems ▼
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Disease Information for Chronic Inflammatory Demyelinating Polyneuropathy (CIDIP)
- Clinical Manifestations
- Signs & Symptoms
- Acute Motor Weakness
- Distal Muscle Weakness
- Distal upper extremity weakness
- Hypotonia
- Absent knee reflexes
- Ankle reflexes decreased
- Ataxia
- Hyporeflexia/DTRs decreased
- Motor and sensory neuropathy/Polyneuropathy signs
- Paralysis
- Sensory Ataxia
- Staggering Gait
- Symmetric Polyneuropathy
- Distal Hyperlaxity
- Marcus-Gunn pupil reaction/consensory sign
- Clinical Presentation & Variations
- Presentation/Progressive Motor Sensory Polyneuropathy
- Disease Progression
- Course/Chronic disorder
- Course/Chronic only
- Laboratory Tests
- Abnormal Lab Findings - Increased
- Anti-Sulfatide Antibody (labs)
- Peripheral neural antibody titer
- CSF IGG synthesis rate
- Diagnostic Test Results
- Other Tests & Procedures
- Lumbar puncture/abnormal
- Pathology
- BX/Nerve biopsy/abnormal
- BX/Nerve biopsy/Inflammatory demyelination
- BX/Nerve biopsy/Patchy demyelination/peripheral nerves
- Electrodiagnosis
- EMG/NCS Demyelination pattern
- EMG/NCS Prolonged distal latencies
- EMG/NCS Slowing
- Associated Diseases & Rule outs
- Rule Outs
- Amyotrophic lateral sclerosis
- Diabetic peripheral neuropathy
- Eaton-Lambert syndrome
- Lead toxicity/poisoning
- Multiple sclerosis
- Peroneal muscular atrophy/Charcot Marie Tooth
- Associated Disease & Complications
- Inflammatory Polyneuropathy Syndrome
- Inflammatory polyneuropathy/demyelinating/chronic
- Mononeuritis, multiplex
- Motor neuropathy
- Multi-radicular Polyneuropathy syndrome
- Polyneuritis
- Ataxia Disorder
- Demyelinating Disease
- Mononeuropathy
- Disease Mechanism & Classification
- Class
- CLASS/Neurologic (category)
- Pathophysiology
- Pathophysiology/Acquired Neuropathy
- Pathophysiology/Delayed nerve conduction velocity
- Pathophysiology/Demyelinating Spares Brain
- Pathophysiology/Demyelination
- Pathophysiology/Peripheral neurologic myelinopathy
- Pathophysiology/Polyradiculneuropathy demyelininating
- Process
- PROCESS/Autoimmune disorder (ex)
- PROCESS/Use/Age/atrophic disorder (category)
- PROCESS/CNS/White matter disorder (ex)
- PROCESS/Mononeuropathy tendency (ex)
- PROCESS/Myelin involvement/disorder (ex)
- Synonyms
- Synonym
- Chr infl demyel plyradiculoneu, CHRONIC INFLAMM DEMYELINATING POLYRADICULONEUROPATHY, CHRONIC INFLAMM POLYRADICULONEUROPATHY, Chronic inflammatory demyelinating polyradiculoneuropathy, Chronic inflammatory demyelinating polyradiculoneuropathy (disorder), Chronic Inflammatory Polyradiculoneuropathies, Chronic Inflammatory Polyradiculoneuropathy, Chronic Inflammatory Polyradiculopathies, Chronic Inflammatory Polyradiculopathy, CIDP, CIDP Chronic inflammatory demyelinating polyradiculoneuropathy, CIDP chr infl demyel polyradic, CIDP chr inflammatory demyelinating polyradiculoneuropathy, INFLAMM POLYRADICULOPATHY CHRONIC, Inflammatory Polyradiculopathies Chronic, Inflammatory Polyradiculopathy Chronic, POLYNEUROPATHY INFLAMMATORY DEMYELINATING CHRONIC, Polyradiculoneuropathies Chronic Inflammatory, POLYRADICULONEUROPATHY CHRONIC INFLAMM, POLYRADICULONEUROPATHY CHRONIC INFLAMM DEMYELINATING, Polyradiculoneuropathy Chronic Inflammatory, Polyradiculoneuropathy Chronic Inflammatory Demyelinating, Polyradiculopathies Chronic Inflammatory, Polyradiculopathy Chronic Inflammatory, Synonym/CIDP/demyelinating polyradiculoneuritis, Synonym/Demyelinating polyradiculoneuop/chr/inflam.
- Treatment
- Drug Therapy - Indication
- RX/Immunoglobulin infusion
- SX/Nerve biopsy
- Other Treatments
- TX/Plasma exchange/FFP
- TX/Plasmapheresis/exchange.
- Definition
-
Chronic Inflammatory Demyelinating Polyneuropathy
Other names or spellings: CIDP, chronic relapsing polyneuropathy; Chronic condition damaging peripheral nerves; Parent types of Chronic Inflammatory Demyelinating Polyneuropathy: Demyelinating disorder; Organs Affected by Chronic Inflammatory Demyelinating Polyneuropathy: nerves, arms, legs, toes, fingers; More common in young adults, but any age possible,and in both genders, CIDP is more common in young adults, and in men more so than women;
Prognosis of Chronic Inflammatory Demyelinating Polyneuropathy: The course of CIDP varies widely among individuals; Some may have a bout of CIDP followed by spontaneous recovery, while others may have many bouts with partial recovery in between relapses; The disease is a treatable cause of acquired neuropathy and initiation of early treatment to prevent loss of nerve cells is recommended; However, some individuals are left with some residual numbness or weakness; Complications of Chronic Inflammatory Demyelinating Polyneuropathy; symptoms of Chronic Inflammatory Demyelinating Polyneuropathy: List of symptoms of Chronic Inflammatory Demyelinating Polyneuropathy: Slowly progressive weakness and sensory dysfunction of the legs and arms; Tingling in toes and fingers; Numbness in toes and fingers; Weakness of the arms and legs; Aching muscle pain; Loss of deep tendon reflexes (areflexia); Fatigue; Abnormal sensations; Treatments: Corticosteroids; Prednisone; Immunosuppressant drugs; Plasmapheresis (plasma exchange); Intravenous immunoglobulin (IVIg) therapy; Physiotherapy; Like GBS, CIDP can improve spontaneously; However, recovery may be very slow and the illness can either get progressively better or worse, or can follow a relapsing/remitting course; Most patients with GBS (Guillian Barre" Syndrome) and CIDP are treated with plasmapheresis or immunoglobulin; Corticosteroids may be used to treat CIDP but are not used to treat GBS, as it worsens rather than improves the condition;
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- External Links Related to Chronic Inflammatory Demyelinating Polyneuropathy (CIDIP)
- Wikipedia
- Merck
- Images
- PubMed (National Library of Medicine)
- NGC (National Guideline Clearinghouse)
- Medscape (eMedicine)
- Harrison's Online (accessmedicine)
- NEJM (The New England Journal of Medicine)