Disease Information for Choriocarcinoma

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Clinical Manifestations
Signs & Symptoms
Breast Pain
Breast pain/soreness/Mastalgia
Bleeding in first trimester
Bleeding in pregnancy
Bleeding in third trimester
Gravid Uterus Pain
Second trimester bleeding
Morning sickness
Amenorrhea
Pelvic pain
Pelvic Pain Chronic
Pelvic Pain Female
Uterine Bleeding
Vaginal Bleeding
Vaginal Bleeding/First Trimester
Vaginal Bleeding/Pregnancy
Vaginal Bleeding/Second Trimester
Weight gain
Disease Progression
Course/Chronic disorder
Course/Chronic only
Demographics & Risk Factors
Event, Activity, Behavioral & Seasonal Factors
Early Morning Events Phenomenon
Sex & Age Groups
Population/Adult/all
Population/Female
Laboratory Tests
Abnormal Lab Findings (Non Measured)
Cytogenetics Abnormal
Cytogenetics Isochromosome 12(i12p) Abnormal
Maternal MSAFP/Quad test (Inhibin A/HG/UE3/AFP)
Maternal triple test (APF/HG/Estriol) abnormal (labs)
MSAFP test (maternal) abnormal (labs)
Testosterone Increased Females
Tumor markers/present (Lab)
Abnormal Lab Findings - Decreased
Human Placental Lactogen (Lab)
Abnormal Lab Findings - Increased
Alpha Fetoprotein, serum (Lab)
Estrogen, serum (Lab)
HCG (beta), serum/Beta sub unit HCG serum (Lab)
Human Placental Lactogen (Lab)
Progesterone (Lab)
Testosterone Total (Lab)
URINE Gonadotropins chorionic
URINE Pregnanediol (Lab)
Diagnostic Test Results
Other Tests & Procedures
Amniocentesis/Placental akaline phosphatase/present
Pathology
BX/Endometrial biopsy/abnormal
PATH/Uterine Dilatation and curettage/abnormal (D&C)
PATH/Trophoblastic cells/specimen
PATH/Syncyticial trophoblast/cytotrophoblast elements
Ultrasound
Ultrasound/Abnormal Placenta scan
Associated Diseases & Rule outs
Rule Outs
Uterine fibroid/leiomyomas
Associated Disease & Complications
Choriocarcinoma
Hydatidiform mole
Hyperthyroid status
Metastasis/malignant
Metastatic liver disease
Peritoneal metastasis
Disease Mechanism & Classification
Class
CLASS/Fetal/conceptual products (category)
CLASS/Ovary/uterus/female genital (category)
Pathophysiology
Pathophysiology/Isochromosome 12(i12p) abnormality
Pathophysiology/Radiosensitive malignancy/relative
Pathophysiology/Paraneoplastic Endocrine Syndrome exists
Pathophysiology/Pseudoprecocious puberty/female
Pathophysiology/Pseudoprecocious puberty/male
Process
PROCESS/Carcinoma (ex)
PROCESS/Chemotherapy responsive cancer (ex)
PROCESS/Germ Cell tumor (ex)
PROCESS/Malignancy/cancer (ex)
PROCESS/Neoplastic (category)
PROCESS/Trophoblastic tumor (ex)
Synonyms
Synonym
Choriocarcinoma, Choriocarcinoma (disorder), Choriocarcinoma (morphologic abnormality), Choriocarcinoma, no ICD O subtype (morphologic abnormality), Choriocarcinomas, Chorioepithelioma, Chorionepithelioma, Syncytioma, Synonym/Chorioendothelioma, Synonym/Metastatic trophoblastic disease, Synonym/MTD/Metastatic trophoblastic disease
Treatment
Drug Therapy - Indication
RX/Alkylating agents
RX/Chemotherapy(cancer)
RX/Chlorambucil (Leukeran)
RX/Dactinomycin (Actinomycin D)
RX/High-dose methotrexate/leukovorin rescue
RX/Methotrexate (Amethopterin)
SX/Hysterectomy
Definition

A rare cancer in women of child-bearing age in which cancer cells grow in the tissues that are formed in the uterus after conception. Also called gestational trophoblastic disease, gestational trophoblastic neoplasia, gestational trophoblastic tumor, or molar pregnancy.

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External Links Related to Choriocarcinoma
Google
Wikipedia
Merck
Images
PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
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