Disease Information for Chloramphenicol (Chloromycetin) Administration/Toxicity

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Clinical Manifestations
Signs & Symptoms
Gray cyanosis/sign
Motor and sensory neuropathy/Polyneuropathy signs
Paresthesias
Laboratory Tests
Abnormal Lab Findings - Decreased
Neutrophiles (Lab)
Platelet count (Lab)
TIBC/Total Iron Binding capacity (Lab)
Transferrin saturation (Lab)
Abnormal Lab Findings - Increased
Hematocrit (Lab)
Iron, serum (Lab)
pH, arterial blood (Lab)
Associated Diseases & Rule outs
Associated Disease & Complications
Acidosis
Acidosis, metabolic
Acute leukemia
Agranulocytosis
Anemia
Anemia, aplastic
Drug induced Anemia.
Drug induced Neutropenia.
Granulocytopenia/Neutropenia
Leukemia
Optic neuritis
Peripheral neuropathy
Polyneuritis
Porphyria, attack, acute intermittant
Sideroblastic Anemia Sideroachrestic
Toxic amblyopia syndrome
Polyneuropathy
Disease Mechanism & Classification
Drugs
DRUG/Anti-anaerobic antibiotic/activity
DRUG/Antibiotic/antibacterial drug (example)
DRUG/Antibiotic/Antimicrobial drugs (category)
DRUG/Bacteriocidal antibiotic (example)
DRUG/Bacteriostatic antibiotic (example)
DRUG/Narrow range of safety (effect/toxic)
DRUG/Older medication/little used
DRUG/Specialized usage (example)
DRUG-Liver metabolism/bile excretion
Process
PROCESS/Medication/Drug (CONFIRM dose/before treatment)
Synonyms
Synonym
(AM150) CHLORAMPHENICOL, (R (R*,R*)) 2,2 Dichloro N (2 hydroxy 1 (hydroxymethyl) 2 (4 nitrophenyl)ethyl)acetamide, 528 CHLORAMPHENICOLS, Acetamide, 2,2 dichloro N (2 hydroxy 1 (hydroxymethyl) 2 (4 nitrophenyl)ethyl) , (R (R*,R*)), Chloramphenicol, Chloramphenicol (class of antibiotic), Chloramphenicol (class of antibiotic, substance) (substance), Chloramphenicol (dup) (substance), Chloramphenicol (ear), Chloramphenicol (ear) (product), Chloramphenicol (ear) (substance), Chloramphenicol (eye), Chloramphenicol (eye) (product), Chloramphenicol (eye) (substance), Chloramphenicol (product), Chloramphenicol (skin), Chloramphenicol (skin) (product), Chloramphenicol (skin) (substance), Chloramphenicol (substance), Chloramphenicol (systemic), Chloramphenicol (systemic) (product), Chloramphenicol (systemic) (substance), chloramphenicol ophthalmic, chloramphenicol otic, CHLORAMPHENICOL PREPARATION, Chloramphenicol product, CHLORAMPHENICOLS, Cloranfenicol, Kloramfenikol, Brand name/A-K-Chlor (Chloramphenicol), Brand name/Chloromycetin (Chloramphenicol), Brand name/Chloromycetin (Chloramphenicol) ophthalmic, Britain-BNF/Kemicetine (Chloramphenicol) injection
Treatment
Drug Therapy - Contraindication
RX/Warfarin (Coumadin)
Drug Dosage
DRUG/.$$$$$ Most Expensive
DRUG/Dose 500 mgm (Unit/Pill/Capsule size)
DRUG/Dose QID Medication
DRUG/Drug discontinued/TOXIC (RX)
DRUG/Injectable medication (parenteral)
DRUG/Intravenous administraton RX
DRUG/IV requires lesser dose/Caution
DRUG/Ophthalmologic/application medication (ex)
DRUG/Oral medication (ex)
Definition

An Antibacterial antibiotic drug; causes bone marrow depression; specialized uses include typhoid and plague

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External Links Related to Chloramphenicol (Chloromycetin) Administration/Toxicity
Google
Wikipedia
Merck
Images
PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
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