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Disease Information for Cataplexy
- Clinical Manifestations
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- Cataplexy-like attacks
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- Pathophysiology/Abnormal hypocretin CNS pathways
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- Definition
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A condition characterized by transient weakness or paralysis of somatic musculature triggered by an emotional stimulus or physical exertion. Cataplexy is frequently associated with NARCOLEPSY. During a cataleptic attack, there is a marked reduction in muscle tone similar to the normal physiologic hypotonia that accompanies rapid eye movement sleep (SLEEP, REM). (From Adams et al., Principles of Neurology, 6th ed, p396)
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- External Links Related to Cataplexy
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- NGC (National Guideline Clearinghouse)
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- Harrison's Online (accessmedicine)
- NEJM (The New England Journal of Medicine)
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