Disease Information for Carotid sinus hypersensitive syncope

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Clinical Manifestations
Signs & Symptoms
Low Blood Pressure
Slow pulse/Bradycardia
Hyperhidrosis/Chronic sweating excess
Sweating Excess Perspiration
Dizziness/Dizzy
Drop attacks
Symptomatic Apparent Seizure
Symptomatic Seizure
Vertigo
Rapid Breathing
Tachypnea/Increased respiratory rate
Collapse/Prostration
Episodic symptoms/events
Falling
Falling/in the elderly/complaint
Pallor
Spells/Episodes of weakness
Vasovagal activation/parasympathetic tone/Signs
Blurred Cloudy Vision
Dimming vision/acute
Disease Progression
Course/Attacks Episodic Spells
Course/Episodic clusters of attacks
Course/Paroxysmal
Demographics & Risk Factors
Established Disease Population
Patient/Trauma effect/occult injury
Population Group
Man
Middle Age Adult
Sex & Age Groups
Population/Adult/all
Population/Fifties adult
Population/Male
Population/Man patient
Population/Middle-aged adult
Population/Sixties-adult
Diagnostic Test Results
Electrodiagnosis
Electrophysiologic/cardiac conduction study abnormal
EKG (ECG)
EKG/Sinus bradycardia (ECG)
Associated Diseases & Rule outs
Rule Outs
Cerebral vascular accident
Convulsions (grand mal)
Epilepsy
Orthostatic hypotension syndrome
Partial complex seizure
Seizure disorder (epilepsy)
Shy-Drager syndrome
Sick sinus syndrome
Temporal/Craniotemporal arteritis
Associated Disease & Complications
Carotid sinus syncope/sensitivity
Hypotension
Neurocardiogenic syncope syndrome
Sinus bradycardia
Syncope, vasovagal
Syncope/Fainting
Disease Mechanism & Classification
Class
CLASS/Cardiovascular (category)
CLASS/Neurologic (category)
Process
PROCESS/Episodic disorder (ex)
PROCESS/Vegetative-Autonomic/Endocrine (category)
Synonyms
Synonym
carotid body or sinus syndrome, Carotid body syndrome, carotid sinus syncope, Carotid sinus syncope (disorder), Carotid Sinus Syncopes, carotid sinus syndrome, Hyperactive carotid sinus reflex syndrome, sinus caroticus syncope, syncope carotid sinus, Syncopes Carotid Sinus, syndrome carotid sinus, TIGHT COLLAR SYNDROME, WEISS BAKER SYNDROME, Synonym/Cardioinhibitory Carotid Sinus Syndrome, Synonym/Carotid Body tumor synd, Synonym/Carotid Sinus hypersensitivity, Synonym/Carotid Sinus Syncope, Synonym/Charcot-Weiss-Baker syndrome, Synonym/Hyperactive Carotid Sinus Reflex, Synonym/Tight Collar syndrome, Synonym/Weiss-Baker Syndrome
Treatment
Drug Therapy - Indication
RX/Atropine
SX/Pacemaker insertion
Other Treatments
TX/Carotid massage.
Definition

Charcot-Weiss-Baker syndrome; Weiss-Baker syndrome; Cardioinhibitory carotid sinus syndrome, Carotid body tumor syndrome, carotid sinus hypersensitivity syndrome, carotid sinus syncope, carotid sinus syndrome, hyperactive carotid sinus reflex syndrome, tight collar syndrome, vagal syncope, vasovagal syndrome; Consists of transient attacks of syncope with marked slowing in heart rate and lowering of blood pressure, and loss of consciousness, caused by strong pressure on the neck over the bifurcation of the carotid arteries, which cause the excitation of baroreceptors of the carotid sinuses; The attacks may also be produced by a sudden turn of the head, wearing a tight collar; Attacks may be preceded or accompanied by focal neurological signs; In some cases the patient dies of heart arrest; Elderly persons, especially those with calcified atherosclerotic plaques in the carotid arteries, are most susceptible; The condition occurs more commonly in men, more often after the age of 45 years

-----------[whonamedit_com 2005]---------- Carotid sinus hypersensitivity (CSH) is an exaggerated response to carotid sinus baroreceptor stimulation; It results in dizziness or syncope from transient diminished cerebral perfusion; Although baroreceptor function usually diminishes with age, some people experience hypersensitive carotid baroreflexes; For these individuals, even mild stimulation to the neck results in marked bradycardia and a drop in blood pressure; CSH predominantly affects older males; a potentially treatable cause of unexplained falls and neurocardiogenic syncopal episodes in elderly people; In CSH, mechanical deformation of the carotid sinus leads to an exaggerated response with bradycardia or vasodilatation, resulting in hypotension, presyncope, or syncope; Three types of CSH have been described: The cardioinhibitory type comprises 70-75% of cases; The predominant manifestation is a decreased heart rate, which results in sinus bradycardia, atrioventricular block, or asystole due to vagal action on sinus and atrioventricular nodes; This response can be abolished with atropine; The vasodepressor type comprises 5-10% of cases; The predominant manifestation is a vasomotor tone decrease without a change in heart rate; This response is not abolished with atropine;

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External Links Related to Carotid sinus hypersensitive syncope
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Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
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