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Disease Information for Carcinomatous neuropathic syndrome

Clinical Manifestations
Signs & Symptoms: Symmetrical muscle/pain, weakness; Weak/Weak as a kitten (symptom)
: Arm distal sensation decrease; Clumsiness/poor coordination; Glove/stocking hypesthesia; Hypesthesia; Loss position sense/postural sense; Paralysis; Paresthesias; Symmetric Polyneuropathy; Weakness/Diffuse motor loss
: Enervated/extreme acute fatigue; Weakness
Disease Progression: Course/Chronic disorder; Course/Chronic only
Demographics & Risk Factors
Established Disease Population: Patient/Cancer
Laboratory Tests
Abnormal Lab Findings (Non Measured): Paraneoplastic Antibody Panel (Lab)
Abnormal Lab Findings - Increased: Anti-CRMP5/Neuronal Cytoplasm antibody; Anti-Hu/ANNA-IIA Paraneoplastic antigen (Lab); Anti-VGCC presynaptic channels
: CSF Anti-Hu (ANNA 2a) antibodies
Diagnostic Test Results
Pathology: BX/Nerve biopsy/Axonal neuropathy
Electrodiagnosis: EMG/NCA Low amplitude; EMG/NCS Prolonged distal latencies; EMG/NCS Slowing; Nerve Conduction Study Abnormal ENG
Associated Diseases & Rule outs
Rule Outs: Diabetic peripheral neuropathy; Eaton-Lambert syndrome; Lead toxicity/poisoning
Associated Disease & Complications: Myelopathy manifestations/involvement; Paraneoplastic syndrome; Peripheral neuropathy; Polyneuritis
: Polyneuropathy
Disease Mechanism & Classification
Class: CLASS/Neurologic (category)
Pathophysiology: Pathophysiology/Acquired Neuropathy; Pathophysiology/Delayed nerve conduction velocity
Process: PROCESS/Autoimmune disorder (ex); PROCESS/Complicating disorder (ex); PROCESS/Neoplastic (category); PROCESS/Paraneoplastic disorder (ex); PROCESS/Paraneoplastic neurologic disorder; PROCESS/Reference organ/system (category)
Synonyms
Synonym: Carcinomatous neuropathy, Carcinomatous peripheral neuropathy, Neuropathies Paraneoplastic, Neuropathies Paraneoplastic Peripheral, NEUROPATHY PARANEOPL, Neuropathy Paraneoplastic, Neuropathy Paraneoplastic Peripheral, PARANEOPL NEUROPATHY, PARANEOPL PERIPHERAL NEUROPATHY, PARANEOPL POLYNEUROPATHY, Paraneoplastic Neuropathies, Paraneoplastic Neuropathy, Paraneoplastic neuropathy (disorder), Paraneoplastic Peripheral Neuropathies, Paraneoplastic Peripheral Neuropathy, Paraneoplastic Polyneuropathies, Paraneoplastic polyneuropathy, Peripheral Neuropathies Paraneoplastic, Peripheral neuropathy carcinomatous, PERIPHERAL NEUROPATHY PARANEOPL, Peripheral Neuropathy Paraneoplastic, Polyneuropathies Paraneoplastic, Polyneuropathy in malignancies, Polyneuropathy in malignancy, Polyneuropathy in malignant disease, POLYNEUROPATHY PARANEOPL, Polyneuropathy Paraneoplastic, Synonym/AntiHu paraneoplastic polyneuropathy variant
Definition: Be the first to add a definition for Carcinomatous neuropathic syndrome
External Links Related to Carcinomatous neuropathic syndrome: Google; Wikipedia; Merck; Images; PubMed (National Library of Medicine); NGC (National Guideline Clearinghouse); Medscape (eMedicine); Harrison's Online (accessmedicine); NEJM (The New England Journal of Medicine)

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