Disease Information for Carboplatin (Paraplatin) Administration/Toxicity

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Clinical Manifestations
Signs & Symptoms
Baldness/Alopecia
Hair loss
Non-scarring Alopecia/balding
Rash
Laboratory Tests
Abnormal Lab Findings - Increased
Platelet count (Lab)
Associated Diseases & Rule outs
Associated Disease & Complications
Agranulocytosis
Anaphylactoid reaction/Non-IGE/Very first dose
Bone marrow failure/exhaustion
Carboplatin (Paraplatin) toxicity
Dermatitis/Chronic rash
Drug induced Baldness/Alopecia
Drug induced Myelosuppression.
Drug induced Neutropenia.
Drug induced Peripheral neuropathy.
Drug induced Rash/eruption/herbal
Drug induced Thrombocytopenia.
Drug rash/Drug induced rash
Fetal anomaly
Granulocytopenia/Neutropenia
Myelosuppression
Peripheral neuropathy
Polyneuritis
Thrombocytopenia
Thrombocytosis
Polyneuropathy
Disease Mechanism & Classification
Drugs
DRUG/Alkylating agents (example)
DRUG/Chemotherapeutics/cancer drugs/etc (category)
DRUG/Cytotoxic/chemotherapy medication (example)
DRUG/Platinum Chemotherapy agents
DRUG/Teratogenic potential/effect (D plus )
Process
PROCESS/Medication/Drug (CONFIRM dose/before treatment)
Synonyms
Synonym
(SP 4 2) diammine(1,1 cyclobutanedicarboxylato(2 ) O,O')platinum, 1,1 cyclobutanedicarboxylic acid platinum complex, Carboplatin, Carboplatin (product), Carboplatin (substance), CARBOPLATIN PREPARATION, Carboplatino, CBDCA, CBDCA Carboplatin, cis diammine(1,1 cyclobutanedicarboxylato) platinum(II), Cis Diammine(cyclobutane 1,1 dicarboxylato)platinum, cis diammine(cyclobutanedicarboxylato)platinum II, DIAMMINECYCLOBUTANEDICARBOXYLATOPLATINUM II, platinum diammine(1,1 cyclobutanedicarboxylato(2 )) (SP 4 2), Brand name/Paraplatin (Carboplatin), Synonym/GemCarbo Chemotheray
Treatment
Drug Dosage
DRUG/Dose special schedule/course
DRUG/Dose Unit dose Vial preparation
DRUG/Injectable medication (parenteral)
DRUG/Intravenous administraton RX
Definition

Platinum toxic effect drug. Primarily an Antineoplastic cancer chemotherapy drug. Alkylating agents interfere with methylation of DNA in mitosis, inhibits cell devision. Speciality use only is recommended; a dangerous class of drugs with predictable bone marrow suppression often.

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External Links Related to Carboplatin (Paraplatin) Administration/Toxicity
Google
Wikipedia
Merck
Images
PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
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