Disease Information for Carbon tetrachloride exposure

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Clinical Manifestations
Signs & Symptoms
Low Blood Pressure
Slow pulse/Bradycardia
Yellow skin discoloration
Abdominal Pain
Abdominal Pain Crampy
Nausea
Vomiting
Fever with Jaundice
Jaundice/Yellow skin and eyes
Palpable Liver/Hepatomegaly
Yellow eyeballs/Scleral icterus
Acute ataxia
Confusion/Disoriented
Dizziness/Dizzy
Intoxicated state/ataxia/slurred speech
Lightheadedness/giddyness/spacey
Slurred Speech/Acute
Staggering Gait
Stupor/poor reponse to stimulus
Unconscious/Narcosis status
Vertigo
Bronchospasm signs
Wheezing
Dark urine
Hematuria, gross
Acutely ill patient/signs
Intoxication/overdose syndrome
Blurred Cloudy Vision
Difficulty Focusing Eyes
Dimming vision/acute
Diplopia Double vision
Clinical Presentation & Variations
Presentation/Fever Jaundice Renal failure Adult male
Disease Progression
Course/Acute
Course/Acute only
Course/Slow curve/Fast break over days
Demographics & Risk Factors
Established Disease Population
Patient/Alcoholism/chronic alcoholic
Laboratory Tests
Microbiology & Serology Findings
Stool Microscopic polys present
Abnormal Lab Findings (Non Measured)
URINE Dipstick /Blood abnormal
Abnormal Lab Findings - Increased
WBC
Bilirubin, serum (Lab)
Indirect bilirubin (Lab)
LDH isoenzyme 5 (Lab)
WBC/White Blood Cell Count/Leukocytes (Lab)
URINE Chlorinated hydrocarbons/Fujiwara test
URINE Red blood cells
Diagnostic Test Results
Pathology
BX/Liver biopsy/Central lobular necrosis
BX/Liver biopsy/Centrilobular necrosis/hepatic congestion
BX/Liver biopsy/Fatty change in liver tissue
BX/Liver biopsy/Foam cells
BX/Liver biopsy/Hepatocyte necrosis
BX/Liver Foamy fatty cells/central nuclei
PATH/Large fatty liver
PATH/Foam cells macrocytic vacuoles
X-RAY
Xray/Radiopaque material/pills in gut/ABD
Associated Diseases & Rule outs
Associated Disease & Complications
Acute anuria/renal failure
Acute hepatic necrosis/yellow atrophy
Acute Renal Failure
Anemia, aplastic
Asthma
Azotemia/Acute
Bilirubinemia
Cardiac arrhythmias
Cirrhosis
Coma/Unconscious
Encephalopathy/CNS effect
Fatty liver
Fetal anomaly
Fulminant hepatic failure
Hepatic necrosis, subacute
Hypotension
Leukocytosis
Noxious gas inhalation/toxicity
Sedation/torpor induced
Toxic hepatitis
Toxic Nephritis/Nephropathy
Ventricular fibrillation
Ventricular tachycardia/arrest
Ataxia Disorder
Hematuria
Disease Synergy - Causes
Synergy/Alcohol recent intake
Synergy/Barbiturates/Chronic RX
Disease Mechanism & Classification
Pathophysiology
Pathophysiology/Hepatic manifestations/involvement
Pathophysiology/Bronchospasm
Process
PROCESS/Poison/specific (category)
Toxin
TOXIN/ Delay/slow curve fast break/over days
TOXIN/Absorbed/skin/eyes/mucous membranes contact
TOXIN/Chlorinated hydrocarbon/solvent (ex)
TOXIN/Gaseous/Fumes/Airborne
TOXIN/Lethal possible
TOXIN/Onset Immediate/Minutes
TOXIN/Poison Organic (category)
TOXIN/Poison/Gaseous/inhaled toxic (category)
TOXIN/Poison/Pesticides/Insecticides (category)
TOXIN/Poison/Solvents/industrial (category)
TOXIN/Radiopague/Ingestion Xray diagnostic potential
TOXIN/Fumigant Gas/Vapor Usage
Treatment
Drug Therapy - Contraindication
RX/Epinephrine (Adrenalin)
Drug Therapy - Indication
RX/Acetylcysteine (Mucomist/NAC) (oral)
RX/N-Acetylcysteine (NAC) IV ?
Definition
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External Links Related to Carbon tetrachloride exposure
Google
Wikipedia
Merck
Images
PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
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