Disease Information for Bupropion (Wellbutrin/Zyban) Administration/Toxicity

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Clinical Manifestations
Signs & Symptoms
Brief Blood pressure increase/sign:
High blood pressure/sign
Hypereactive/on exam
Seizures
Agitation
Hypomanic state
Short attention span
Weight Loss
Associated Diseases & Rule outs
Associated Disease & Complications
Convulsions (grand mal)
Drug induced Agitation/Hyperactivity/Hypomania.
Drug induced Hypertension.
Drug induced Seizures
Hypertension
Hypomania
Disease Mechanism & Classification
Drugs
DRUG/Anti-addiction medication (example)
DRUG/Antidepressant medication (examples)
DRUG/Psychoactive/sedative drug (category)
DRUG/Safe in pregnancy patient (B)
DRUG/Lowers seizure threshold
Process
PROCESS/Medication/Drug (CONFIRM dose/before treatment)
Synonyms
Synonym
(+ ) 1 (3 Chlorophenyl) 2 ((1,1 dimethylethyl)amino) 1 propanone, 1 Propanone 1 (3 chlorophenyl) 2 ((1,1 dimethylethyl)amino), admin, Amfebutamone, BUP, buPROPion, Bupropion (dup) (substance), Bupropion (product), Bupropion (substance), BUPROPION PREPARATION, Brand name/Empatic (Bupropion-Zonisamide) Combination, Brand name/Wellbutrin (Bupropion), Brand name/Zyban (Bupropion)
Treatment
Drug Dosage
DRUG/.$$$ Expensive medication
DRUG/.1990 or before
DRUG/Dose 100 mgm (Unit/Pill/Capsule size)
DRUG/Dose 150 mgms (Unit/Pill/Capsule size)
DRUG/Dose 75 Mgm (Unit/Pill/Capsule size)
DRUG/Dose BID Medication
DRUG/Dose Extended time release/XT/SA (example)
DRUG/Dose TID Medication
DRUG/Generic available
DRUG/Injection Preparation NOT available
DRUG/Oral medication (ex)
Definition

Anti-depressant drug; unique separate class and mechanism; an aminoketone drug; lowers seizure threhold and has many drug-drug interactions; oral preparation only; (aminoketone)

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External Links Related to Bupropion (Wellbutrin/Zyban) Administration/Toxicity
Google
Wikipedia
Merck
Images
PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
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