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Disease Information for Blast crises of chronic leukemia

Clinical Manifestations
Signs & Symptoms: Bleeding from Mouth in Elderly; Bleeding from mouth/oral blood; Bleeding gums; Oral lesion/ulcer; Oral Ulcers in Elderly
: Lymphadenopathy Systemic
: Bone Pains; Sternal swelling; Sternal tenderness
: Epistaxis, severe/persistent
: Splenomegaly
: Acutely ill patient/signs; Chronic Fatigue; Constitutional symptoms; Fever; Fever Febrile Possible; Fever one week/non-infectious; Flu-Like Syndrome; High body temperature; Pallor; Weight Loss
: Dry eyes/poor tearing; Dry eyes/Poor tearing in Elderly; Dryness Conjunctiva; Grainy/Gritty Eye Sensation
Clinical Presentation & Variations: Fever and High Sed Rate
Disease Progression: Course/Acute; Course/Chronic disorder
: Pancytopenia with Hypercellular Marrow
Demographics & Risk Factors
Established Disease Population: Patient/Myelodysplastic process
Laboratory Tests
Abnormal Lab Findings (Non Measured): Cytogenetics Abnormal
: Acute inflammatory markers elevated (Lab); Blast forms/peripheral smear (Lab); Diagnostic Blood Smear
Abnormal Lab Findings - Decreased: Hematocrit (Lab); Hemoglobin (Lab); Leukocyte Alkaline phosphatase (Lab); RBC/Red Blood Count (Lab)
Abnormal Lab Findings - Increased: Hemoglobin (Lab); Platelet count (Lab); Sed Rate/ESR/Sedimentation rate (Lab)
Diagnostic Test Results
Pathology: Bone Marrow/Abnormal; Bone marrow/Blasts increased; Bone marrow/Blasts infiltrating/Leukemic pattern; Bone Marrow/Ratio myeloproliferative increase
Associated Diseases & Rule outs
Rule Outs: Anemia, aplastic
Associated Disease & Complications: Acute leukemia; Anal fissure; Anemia; Anemia, aplastic; Bleeding diathesis/hemorrhagic diathesis; Bleeding Tendency; Bone Marrow Fibrosis; Cancer in Elderly; Epistaxis/nosebleed; Leukemic blast crisis; Leukostasis syndrome/hyperleukocytosis; Myeloblastic crisis, acute/Chr.Myel.Leukemia; Myelofibrosis; Myelofibrosis secondary; Pancytopenia; Thrombocytopenia; Thrombocytopenia in Elderly; Thrombocytosis
: Anemia in Elderly
Disease Mechanism & Classification
Class: CLASS/Hematologic (category); CLASS/Leukocyte involvement/disorder (ex); CLASS/Marrow involvement/disorder (ex)
Process: PROCESS/Complicating disorder (ex); PROCESS/Complicating/Specific process disorder (ex); PROCESS/Neoplastic (category)
: PROCESS/Blood dyscrasia/leukemic process (ex); PROCESS/Leukemia process (ex).
Treatment
Drug Therapy - Indication: RX/Chemotherapy(cancer); RX/Imatinib (Gleevec/Glivec); SX/Stem cell transplant/allogenic; SX/Stem cell transplant/autologous; SX/Stem-cell transplant
Other Treatments: TX/Medical emergency
Definition: Be the first to add a definition for Blast crises of chronic leukemia
External Links Related to Blast crises of chronic leukemia: Google; Wikipedia; Merck; Images; PubMed (National Library of Medicine); NGC (National Guideline Clearinghouse); Medscape (eMedicine); Harrison's Online (accessmedicine); NEJM (The New England Journal of Medicine)

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