Disease Information for Bisphosphonate therapy

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Laboratory Tests
Abnormal Lab Findings - Increased
URINE N-Telopeptide Crosslinks levels
Associated Diseases & Rule outs
Associated Disease & Complications
Esophagitis
Esophagitis, reflux/GERD
Gastritis, erosive/corrosive
Hyperphosphatemia
Jaw necrosis/mandible
Osteoradionecrosis Jaw
Disease Mechanism & Classification
Drugs
DRUG/Bisphosphonate drug (example)
Process
PROCESS/Medication/Drug (CONFIRM dose/before treatment)
Treatment
Drug Dosage
DRUG/Injectable medication (parenteral)
DRUG/Intravenous administraton RX
DRUG/Oral medication (ex)
Definition

Bisphosphonates have become the treatment of choice for Paget"s disease. The oral compounds should all be taken with 8 oz of plain water only. Bisphosphonates are usually given cyclically. Therapy is given until a therapeutic response occurs, as evidenced by normalization of the serum alkaline phosphatase. Patients are then given a break from therapy for about 3 months or until the serum alkaline phosphatase becomes elevated again; another cycle is then commenced.

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External Links Related to Bisphosphonate therapy
Google
Wikipedia
Merck
Images
PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
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