Disease Information for Binswanger's dementia

NINDS Binswanger"s Disease;Subcortical Arteriosclerotic Encephalopathy, Dementia - Subcortical;Binswanger"s disease, sometimes referred to as subcortical dementia, is a rare form of dementia characterized by cerebrovascular lesions in the deep white-matter of the brain, loss of memory and cognition, and mood changes; Patients usually show signs of abnormal blood pressure, stroke, blood abnormalities, disease of the large blood vessels in the neck, and disease of the heart valves; Other prominent features of the disease include urinary incontinence, difficulty walking, clumsiness, slowness of conduct, lack of facial expression, and speech difficulty; These symptoms, which tend to begin after the age of 60, are not always present in all patients and may sometimes appear only as a passing phase; There is no specific course of treatment for Binswanger"s disease; Treatment is symptomatic, often involving the use of medications to control high blood pressure, depression, heart arrhythmias and low blood pressure; Binswanger"s disease is a slowly progressive condition for which there is no cure; The disorder is often marked by strokes and partial recovery.

[NINDS/NIH 2005]------------------------------------Binswanger"s Disease; Binswanger"s Encephalopathy

Multi-infarct Dementia, Binswanger"s Type; SAE; Subcortical Dementia ; Subcortical Ischemic Vascular Disease;

Vascular Dementia, Binswanger"s Type

Binswanger"s disease is a rare, progressive neurological disorder characterized by injuries (lesions) to the blood vessels supplying the deep white-matter of the brain; Affected individuals usually experience a gradual loss of memory, cognitive, and behavioral abilities, usually over a ten-year period; In some cases, symptoms and physical findings associated with Binswanger"s disease may stabilize or improve for a brief time; however, in most cases, progression of the disorder usually returns; Affected individuals experience progressive memory loss and deterioration of intellectual abilities (dementia), strokes, paralysis of one or the other side of the body (hemiparesis), electrical disturbance in the brain (seizures), and/or an abnormally slow, unsteady walk (abnormal gait)---------------- [NORD 2005]---------------

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