Disease Information for Azathioprine (Imuran) Administration/Toxicity

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Clinical Manifestations
Clinical Presentation & Variations
Presentation/Pancreatitis Kids Recurrent
Demographics & Risk Factors
Established Disease Population
Patient/Heart transplant
Laboratory Tests
Abnormal Lab Findings (Non Measured)
Leukopenia
Macrocytosis/smear (Lab)
Abnormal Lab Findings - Decreased
WBC
IGM/Immunoglobulin M (Lab)
Neutrophiles (Lab)
WBC/White Blood Cell Count/Leukocytes (Lab)
Abnormal Lab Findings - Increased
Platelet count (Lab)
Diagnostic Test Results
Other Tests & Procedures
Skin test anergy
Pathology
Bone Marrow/Maturation arrest/granulocytes
BX/Liver biopsy/Hepatic venules thrombosed
Associated Diseases & Rule outs
Associated Disease & Complications
Anergic status
Cellular immunity defect/deficiency
Drug induced Chronic Meningitis/inflammatory
Drug induced Hepatitis, idiosyncratic
Drug induced Myelosuppression.
Drug induced Pancreatitis
Granulocytopenia/Neutropenia
Immune suppressed status
Infections
Meningitis, chronic
Myelosuppression
Pancreatitis, acute
Thrombocytopenia
Thrombocytosis
Toxic hepatitis
Veno-occlusive hepatic disease
Disease Mechanism & Classification
Drugs
DRUG/Anti-Rejection Med/Organ transplant
DRUG/Anti-rheumatoid arthritis drug (example)
DRUG/Chemotherapeutics/cancer drugs/etc (category)
DRUG/DMARD/Disease modifying rheumatoid arthritis drug (example)
DRUG/Immune modulator drug (ex)
DRUG/Immune response modifier effect
DRUG/Immune suppressant drug (example)
DRUG/Prevents transplant/allograft rejection
DRUG/Purine antagonists (example)
DRUG/Purine Synthesis Inhibitor
DRUG/RNA Immune modulator drug (ex)
DRUG/Teratogenic potential/effect (D plus )
DRUG-Liver metabolism/bile excretion
Pathophysiology
Pathophysiology/Chronic intrinsic restrictive lung
Process
PROCESS/Medication/Drug (CONFIRM dose/before treatment)
Synonyms
Synonym
1H Purine 6 ((1 methyl 4 nitro 1H imidazol 5 yl)thio), 6 ((1 Methyl 4 nitro 1H imidazol 5 yl)thio) 1H purine, AZA, Azathioprine, Azathioprine chemical, Azathioprine (gastrointestinal), Azathioprine (gastrointestinal) (product), Azathioprine (gastrointestinal) (substance), Azathioprine (gi), Azathioprine (immunosuppress), Azathioprine (immunosuppressant), Azathioprine (product), Azathioprine (substance), AZATHIOPRINE PREPARATION, Azothioprine, AZT Azathioprine, AZTP, Brand name/Imuran (Azathioprine)
Treatment
Drug Therapy - Contraindication
RX/Allopurinol (Zyloprim)
Drug Dosage
DRUG/.1990 or before
DRUG/Dose 50 mgm (Unit/Pill/Capsule size)
DRUG/Dose once daily (RX)
DRUG/Generic available
Definition

Purine antagonist antimetabolite chemotherapy drug used as immune suppressant for RA and inflammatory bowel disease and other auto-immune states; oral and parenteral preparations

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External Links Related to Azathioprine (Imuran) Administration/Toxicity
Google
Wikipedia
Merck
Images
PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
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