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Disease Information for Arteriosclerosis/lower extremity

Clinical Manifestations
Signs & Symptoms: Acute Limb ischemia; Cardiac Symptoms/Signs; Claudication; Decreased peripheral pulses; Dependent rubor/extremity; Dorsalis pedis pulse decreased; Leg claudication; Popliteal pulse decreased; Posterior tibial pulse decreased; Postural color changes extremities; Regional pallor/vasospasm; Unilateral livedo reticularis/extremity; Vasospasm of extremities/Signs
: Leg Ulcers in Elderly; Mottled legs
: Leg Pain with Exercise; Leg/lower extremity pains; Unilateral leg swelling
: Burning feet; Paresthesias
: Tobacco Habit/Excess
: Decreased exercise tolerance/effort fatigue; Poor Stamina
: Arcus senilis/Clouded limbus eye; AV-nicking retinal exam
Clinical Presentation & Variations: Presentation/Painful Leg Ulcer Chronic
Disease Progression: Course/Chronic disorder
Demographics & Risk Factors
Past History: Past history/Aortic surgery/remote; Past history/Myocardial infarct
Established Disease Population: Patient/Diet/High fat history; Patient/Homocystinemia; Patient/Hypercholesterolemia; Patient/Hyperlipidemia
: Patient/Aortic aneurysm/Aortic arteriosclerosis; Patient/Aorticoiliac arteriosclerosis; Patient/Arteriosclerosis; Patient/Arteriosclerosis/lower extremities; Patient/Arteriosclerotic heart disease
: Patient/Cerebral thrombosis
: Patient/Type I/diabetic (juvenile)
Family History: Family history/Hypercholesterolemia/lipidemia
: Family history/Myocardial infarction/CAD
Sex & Age Groups: Population/Adult Aged Only; Population/Adult/all
Laboratory Tests
Abnormal Lab Findings (Non Measured): Apo A/Apo B Ratio lipoprotein Decreased (Lab)
: Apolipoproteins Apo A-1/Apo B Ratio Abnormal; Intercellular adhesion molecule levels/abnormal; Specific Single Nucleotide Polymorphism/SNIP genome type; Total Antioxidant capacity abnormal
Abnormal Lab Findings - Increased: Anti-Oxidized LDL antibody (labs)
: Apo B-100 lipoprotein Level (Lab); Apo B-48 lipoprotein Level (Lab); Apo Lp a (Little a) lipoprotein Level (Lab)
: ApoLipo EE variant (marker) (Lab); Apolipoprotein B Level; Apolipoproteins Apo A-1 (Lab); ApoLP/B-little a (marker) (Lab); Cholesterol (Lab); C-reactive protein (Lab); F2-Isoprostanes (Oxidative stress marker) level; Highly sensitive CRP (LAB); Homocysteine serum (Lab); Serum Amyloid A (SSA)
Diagnostic Test Results
Other Tests & Procedures: Extremity Plethsmography Abnormal; Impedence Body Plethsmography Abnormal; Plethysmography Arterial Abnormal; TEST/Ankle/Brachial doppler ratio/pressure/abnormal; TEST/Doppler flow studies/peripheral abnormal; TEST/Plethysmography/extremities abnormal
CT Scan: CT/Dexa-Scan Bone density Abnormal
Angiography: Angios/Femoral/iliac artery occlusion; Angios/Peripheral arteriogram/abnormal
Associated Diseases & Rule outs
Associated Disease & Complications: Arteriosclerosis, lower extremities; Embolism, atheromatous; Male osteoporosis syndrome; Osteoporosis/osteopenia; Pathologic fractures; Peripheral neuropathy; Polyneuritis; Restless legs syndrome
: Gangrene extremities
: Leg ulcers
: Polyneuropathy
: Metabolic Bone Disease
Disease Synergy - Causes: Synergy/Tobacco smoking
Disease Mechanism & Classification
Class: CLASS/Vascular disorder (ex).
: CLASS/Extremities/Digits/Hand feet disorder (category); CLASS/Muscle/tendon/extremities (category)
Pathophysiology: Pathophysiology/Osteoporosis Secondary
Process: PROCESS/Arteriosclerosis/vascular/venous (category); PROCESS/Complicating disorder (ex); PROCESS/Ischemic process (ex)
Treatment
Drug Therapy - Indication: RX/Anti-platelet/anticoagulant; RX/Cilostazol (Pletal); RX/Low-dose aspirin; RX/Pentoxafylline (Trental); RX/Salicylate/aspirin
Surgical Procedures or Treatments: SX/Surgery
Definition: Be the first to add a definition for Arteriosclerosis/lower extremity
External Links Related to Arteriosclerosis/lower extremity: Google; Wikipedia; Merck; Images; PubMed (National Library of Medicine); NGC (National Guideline Clearinghouse); Medscape (eMedicine); Harrison's Online (accessmedicine); NEJM (The New England Journal of Medicine)

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