Disease Information for Anagrelide (Agrylin) Administration/Toxicity

Ads
Clinical Manifestations
Signs & Symptoms
Bilateral ankle swelling
Bilateral leg edema/swelling
Edema of Lower Extremities
Laboratory Tests
Abnormal Lab Findings - Increased
Platelet count (Lab)
Associated Diseases & Rule outs
Associated Disease & Complications
Bleeding diathesis/hemorrhagic diathesis
Bleeding Tendency
Congestive heart failure
Drug induced Cardiomyopathy/Cardiotoxicity.
Drug induced Hepatic toxicity
Drug induced Thrombocytopenia.
Edema
Thrombocytopenia
Thrombocytosis
Toxic hepatitis
Toxic Nephritis/Nephropathy
Disease Mechanism & Classification
Drugs
DRUG/ Source rDNA Manufacture
DRUG/Antiplatelet/effect medication (example)
DRUG/Chemotherapeutics/cancer drugs/etc (category)
DRUG/Genetically engineered/biological drug (example)
DRUG/Specialized usage (example)
DRUG/Teratogenic/OBGYN Class X/Pregnancy DANGER
Pathophysiology
Pathophysiology/Myocardium Toxic Effect
Pathophysiology/Megakaryopoetic suppression
Process
PROCESS/Medication/Drug (CONFIRM dose/before treatment)
Synonyms
Synonym
Anagrelide (Agrylin) admin, Brand name/Agrylin (Anagrelide)
Treatment
Drug Dosage
DRUG/.$$$$$ Most Expensive
DRUG/Dose 0.5 mgm (Unit/Pill/Capsule size)
DRUG/Dose 1 mgm (Unit/Pill/Capsule size)
DRUG/Dose must be titrated to effect
DRUG/Dose QID Medication
DRUG/Oral medication (ex)
-Pharmacology/Metabolized in liver
Definition

Bioengineered chemotherapy drug bone marrow suppressant thrombocytosis;used in essential thrombocytosis and thrombocytosis from leukemia (myeloproliferative)

(Edit)

External Links Related to Anagrelide (Agrylin) Administration/Toxicity
Google
Wikipedia
Merck
Images
PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
Ads