Disease Information for Altretamine (HMM/Hexalen) Administration/Toxicity

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Associated Diseases & Rule outs
Associated Disease & Complications
Fetal anomaly
Peripheral neuropathy
Polyneuritis
Polyneuropathy
Disease Mechanism & Classification
Drugs
DRUG/Alkylating agents (example)
DRUG/Anti-neoplastic medications (examples)
DRUG/Chemotherapeutics/cancer drugs/etc (category)
DRUG/Cytotoxic/chemotherapy medication (example)
DRUG/H-CAP protocol (four drugs) (comb)
DRUG/Neurotoxicities/drug effect
DRUG/Teratogenic potential/effect (D plus )
Process
PROCESS/Medication/Drug (CONFIRM dose/before treatment)
Synonyms
Synonym
1,3,5 Triazine 2,4,6 triamine N,N,N',N',N'',N'' hexamethyl, 2,4,6 Tris(dimethylamino) s triazine, admin, Altretamine, Altretamine chemical, Altretamine (product), Altretamine (substance), ALTRETAMINE PREPARATION, Hemel, Hexaloids, Hexamethyl melamine, hexamethylmelamine, HMM, HXM, N,N,N',N',N,N hexamethyl 1,3,5 triazine 2,4,6 triamine, N,n,n',NN hexamethyl 1,3,5, triazine 2,4,6, triamine, s Triazine 2,4,6 tris(dimethylamino), Brand name/Hexalen (Altretamine), Brand name/Hexastat (Altretamine), Brand name/HXM (Altretamine), Synonym/Hexamethylmelamine chemical name/admin'n, Synonym/HMM administration
Treatment
Drug Therapy - Contraindication
RX/Monoamine oxidase inhibitor
RX/Pyridoxine (Vitamin B6)
Drug Dosage
DRUG/.$$$$$ Most Expensive
DRUG/Oral medication (ex)
Definition

Primarily an Antineoplastic cancer chemotherapy drug. Alkylating agents interferes with methylation of DNA in mitosis, inhibits cell division. Speciality use only is recommended; a dangerous class of drugs with predictable bone marrow suppression often.

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External Links Related to Altretamine (HMM/Hexalen) Administration/Toxicity
Google
Wikipedia
Merck
Images
PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
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