- Differential Diagnosis
- Diseases
- Drugs
- More
-
- Try building your search one term at a time, and be as specific as you can! Search term example: "chronic cough".
- Do not enter multiple findings such as "anemia, chronic cough, weight loss, vomiting" all at the same time.
- After selecting your term from the search results a list of possible diagnoses will be generated. If the list is too long, you will be able to narrow it down by entering additional terms.
- Do not enter values such as "heart rhythm 110" or "sodium 125", instead use "tachycardia" or "hyponatremia".
- Disease Information
- Disease Comparison
-
Disease Processes ▼
- Auto Immune
- Vascular-Arteriosclerosis
- Biochemical
- Congenital-developmental
- Deficiency
- Degenrative-Necrosis
- Electromagnetic-Physics
- Eponymic
- Functional-Physiologic
- Hereditofamilial
- Iatrogenic
- Idiopathic
- Infected Organ-Abcess
- Infectious agent
- Inflammatory-Granulomatous
- Metabolic-Storage
- Neoplastic
- Poison Agent
- Poisoned Organ
- Radiation-Xray-trauma
- Mental
- Structural-Anatomic-Foreign body
- Surgical Procedure-Complication
- Trauma
- Use-age-Atrophic
- Endocrine-Vegetative
-
Major Organs-Systems ▼
- Systemic
- Pediatric
- Nervous & Sensory System (Neurology)
- Cardiovascular System
- Respiratory (Pulmonary) System
- Gastro-Intestinal (Digestive) System
- Urinary System
- Dermatologic System
- Endocrine System
- Immune System
- Musculoskeletal System
- Genital Reproductive System
- Hematopoietic System (Hematology)
- Lymphatic System
- Tissue/Cells/Organelles
Disease Information for Alpers cerebral degeneration of infancy
- Clinical Manifestations
- Signs & Symptoms
- Central Facial Paralysis
- Equinus Posture/Ankles
- Infant Seizures
- Seizures
- Seizures/Children/recurrent
- Spastic paralysis/signs
- Spasticity/Spastic gait
- Clinical Presentation & Variations
- Presentation/Progressive dementia Child Infant
- Disease Progression
- Course/Chronic disorder
- Course/Chronic only
- Course/Prognosis bad/usually
- Course/Progressive
- Onset/1-5 years old
- Onset/Infancy
- Demographics & Risk Factors
- Population Group
- Child
- Population/Pediatrics population
- Family History
- Family history/Childhood CNS degenerating disease/death
- Sex & Age Groups
- Population/Child
- Population/Child-Infant Only
- Population/Children/all
- Laboratory Tests
- Abnormal Lab Findings - Increased
- Lactic acid/Lactate (Lab)
- pH, arterial blood (Lab)
- Associated Diseases & Rule outs
- Associated Disease & Complications
- Acidosis
- Acidosis, metabolic
- Alpers cerebral degeneration of infancy
- Ascites in Children
- Chronic liver disease
- Cirrhosis
- Cirrhosis in childhood
- Cirrhosis/complication/secondary
- Cognitive/learning disability
- Congenital cataracts
- Convulsions (grand mal)
- Dementia
- Lactic acidosis
- Microcephaly/oligophrenia
- Poliodystrophy/congenital
- Spinal cord lesion/dysfunction
- Upper GI Bleeding in children
- Disease Mechanism & Classification
- Class
- CLASS/Pediatric disorders (ex)
- CLASS/Liver involvement/disorder (ex)
- CLASS/Brain/CNS disorder (ex)
- CLASS/Neurologic (category)
- CLASS/Spinal cord disorder (ex)
- Pathophysiology
- Pathophysiology/Gene locus 15q25
- Pathophysiology/Gene locus Chromosome 15
- Pathophysiology/Gene Locus Identified/OMIM database
- Pathophysiology/Genomic indentifiers (polymorphism/snip/mutations)
- Pathophysiology/Congenital Brain malformation
- Process
- PROCESS/Hereditary mitochondrial disorder (ex)
- PROCESS/INCIDENCE/Rare disease (ex)
- PROCESS/Mitochondrial disorders (ex)
- Synonyms
- Synonym
- Alper Disease, ALPER SYNDROME, Alpers, ALPERS DIFFUSE DEGENERATION OF CEREBRAL GRAY MATTER WITH HEPATIC CIRRHOSIS, ALPERS DIS, Alper's Disease, Alpers' Disease, Alpers' disease or gray matter degeneration, ALPERS HUTTENLOCHER SYNDROME, ALPERS PROGRESSIVE INFANTILE POLIODYSTROPHY, Alpers Syndrome, Alper's Syndrome, Alpers' Syndrome, degeneration gray matter, degeneration grey matter, Disease Alpers', gray matter degeneration, grey matter degeneration, NEURONAL DEGENERATION OF CHILDHOOD WITH LIVER DISEASE PROGRESSIVE, PNDC, Poliodystrophy, Prog neur degen liver cirrho, Progressive degeneration cerebral gray matter, Progressive neuronal degeneration with liver cirrhosis, Progressive sclerosing poliodystrophy, Progressive sclerosing poliodystrophy (disorder), Spongy glioneuronal dystrophy, Syndrome Alpers, Synonym/Alpers Diffuse cerebral grey matter/hepatic cirrhosis, Synonym/Alpers disease variant, Synonym/Alpers Progressive infantile Poliodystrophy, Synonym/Diffuse cerebral degeneration in infancy/Alpers, Synonym/Hereditary mitochondrial disease/Alpers type, Synonym/Poliodystrophia Cerebri Progressiva, Synonym/Progressive Cerebral Poliodystrophy
- Definition
-
Alpers Disease; Alpers Diffuse Degeneration of Cerebral Gray Matter with Hepatic Cirrhosis; Alpers Progressive Infantile Poliodystrophy; Diffuse Cerebral Degeneration in Infancy; Poliodystrophia Cerebri Progressiva; Progressive Cerebral Poliodystrophy.
Discussion: Alpers Disease is a progressive neurologic disorder that begins during childhood; Symptoms include increased muscle tone with exaggerated reflexes (spasticity), seizures, loss of cognitive ability (dementia) and, in many cases, liver disease; [NORD 2005]
(Edit)
- External Links Related to Alpers cerebral degeneration of infancy
- Wikipedia
- Merck
- Images
- PubMed (National Library of Medicine)
- NGC (National Guideline Clearinghouse)
- Medscape (eMedicine)
- Harrison's Online (accessmedicine)
- NEJM (The New England Journal of Medicine)
This site is designed primarily as a reminder system for use by qualified physicians and other medical professionals. By using this site you understand and accept that DiagnosisPro.com shall not be used as a diagnostic decision-making system and must not be used to make a clinical diagnosis or replace or overrule a licensed health care professional's judgment or clinical diagnosis (full terms of use). This site complies with the HONcode standard for trustworthy health information: verify here.
© 2013 MedTech USA, Inc. (last modified on 05/20/13)
