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Disease Information for Alopecia areata

Clinical Manifestations

Signs & Symptoms

Baldness/Alopecia

Beau's lines/Mees lines fingernails

Depigmented patches, skin

Hair loss

Longitudinal grooved nails

Nail Striations

Nails pitting

Non-scarring Alopecia/balding

Scalp hair sparse/thin

Laboratory Tests

Abnormal Lab Findings - Increased

Anti-adrenal cortex antibody (Lab)

Antimicrosomal antibodies (Lab)

Anti-parietal cell antibody (Lab)

Antithyroglobulin antibodies (Lab)

Antithyroid microsomal antibodies (Lab)

Anti-thyroid peroxidase (TPO) antibody (Lab)

Associated Diseases & Rule outs

Rule Outs

Tinea capitis

Associated Disease & Complications

Alopecia areata

Vitiligo

Disease Mechanism & Classification

Class

CLASS/Dermatologic/Subcutaneous (category)

CLASS/Hair involvement/disorder (ex)

CLASS/Scalp involvement/disorder (ex)

Pathophysiology

Pathophysiology/Cytokine gene polymorphism

Pathophysiology/Genomic indentifiers (polymorphism/snip/mutations)

Process

PROCESS/Allergy/collagen/autoimmune (category)

PROCESS/Autoimmune disorder (ex)

PROCESS/Reference organ/system (category)

Treatment

Drug Therapy - Indication

RX/Cortisone/steroid injection locally

Definition

A microscopically inflammatory, usually reversible, patchy hair loss occurring in sharply defined areas and usually involving the beard or scalp (Dorland, 27th ed)-----------------------Alopecia Areata; Alopecia Celsi; Alopecia Cicatrisata; Alopecia Circumscripta; Cazenave"s Vitiligo

Celsus" Vitiligo; Jonston"s Alopecia; Porrigo Decalvans;

Vitiligo Capitis; Variants: Alopecia Seminuniversalis; Alopecia Totalis; Alopecia Universalis; Alopecia areata is a disorder characterized by loss of hair; Sometimes, this means simply a few bare patches on the scalp; In other cases, hair loss is more extensive; Although the exact cause is not known, this is thought to be an autoimmune disorder in which the immune system, the body’s own defense system, mistakenly attacks the hair follicles, the tiny structures from which hairs grow; Unpredictable hair loss is the only noticeable symptom of this disorder; Regrowth of hair may or may not occur; Hair loss is usually confined to the head and face, although the entire body may be involved---------[NORD 2005]---------------

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External Links Related to Alopecia areata

PubMed (National Library of Medicine)

NGC (National Guideline Clearinghouse)

Medscape (eMedicine)

Harrison's Online (accessmedicine)

NEJM (The New England Journal of Medicine)

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