Disease Information for Alopecia areata

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Clinical Manifestations
Signs & Symptoms
Baldness/Alopecia
Beau's lines/Mees lines fingernails
Depigmented patches, skin
Hair loss
Longitudinal grooved nails
Nail Striations
Nails pitting
Non-scarring Alopecia/balding
Scalp hair sparse/thin
Laboratory Tests
Abnormal Lab Findings - Increased
Anti-adrenal cortex antibody (Lab)
Antimicrosomal antibodies (Lab)
Anti-parietal cell antibody (Lab)
Antithyroglobulin antibodies (Lab)
Antithyroid microsomal antibodies (Lab)
Anti-thyroid peroxidase (TPO) antibody (Lab)
Associated Diseases & Rule outs
Rule Outs
Tinea capitis
Associated Disease & Complications
Alopecia areata
Vitiligo
Disease Mechanism & Classification
Class
CLASS/Dermatologic/Subcutaneous (category)
CLASS/Hair involvement/disorder (ex)
CLASS/Scalp involvement/disorder (ex)
Pathophysiology
Pathophysiology/Cytokine gene polymorphism
Pathophysiology/Genomic indentifiers (polymorphism/snip/mutations)
Process
PROCESS/Allergy/collagen/autoimmune (category)
PROCESS/Autoimmune disorder (ex)
PROCESS/Reference organ/system (category)
Treatment
Drug Therapy - Indication
RX/Cortisone/steroid injection locally
Definition

A microscopically inflammatory, usually reversible, patchy hair loss occurring in sharply defined areas and usually involving the beard or scalp (Dorland, 27th ed)-----------------------Alopecia Areata; Alopecia Celsi; Alopecia Cicatrisata; Alopecia Circumscripta; Cazenave"s Vitiligo

Celsus" Vitiligo; Jonston"s Alopecia; Porrigo Decalvans;

Vitiligo Capitis; Variants: Alopecia Seminuniversalis; Alopecia Totalis; Alopecia Universalis; Alopecia areata is a disorder characterized by loss of hair; Sometimes, this means simply a few bare patches on the scalp; In other cases, hair loss is more extensive; Although the exact cause is not known, this is thought to be an autoimmune disorder in which the immune system, the body’s own defense system, mistakenly attacks the hair follicles, the tiny structures from which hairs grow; Unpredictable hair loss is the only noticeable symptom of this disorder; Regrowth of hair may or may not occur; Hair loss is usually confined to the head and face, although the entire body may be involved---------[NORD 2005]---------------

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External Links Related to Alopecia areata
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Wikipedia
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PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
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