Disease Information for Alkylating agent Administration/Toxicity

Ads
Clinical Manifestations
Signs & Symptoms
Baldness/Alopecia
Hair loss
Non-scarring Alopecia/balding
Disease Progression
Pancytopenia with Hypocellular Marrow
Laboratory Tests
Abnormal Lab Findings - Decreased
Neutrophiles (Lab)
Associated Diseases & Rule outs
Associated Disease & Complications
Acute Myelogenous/Myeloblastic Leukemia AML
Agranulocytosis
Alveoloproteinosis, pulmonary
Anemia
Bone marrow failure/exhaustion
Drug induced Anemia.
Drug induced Baldness/Alopecia
Drug induced Neutropenia.
Drug induced Thrombocytopenia.
Granulocytopenia/Neutropenia
Myelosuppression
Pancytopenia
Disease Mechanism & Classification
Drugs
DRUG/Chemotherapeutics/cancer drugs/etc (category)
DRUG/Teratogenic potential/effect (D plus )
DRUG/Teratogenic/OBGYN Class X/Pregnancy DANGER
Process
PROCESS/Medication/Drug (CONFIRM dose/before treatment)
Toxin
TOXIN/Potential carcinogen
Synonyms
Synonym
administration, Agents Alkylating, Alkylating Activity, Alkylating Agent, Alkylating agent (product), Alkylating agent (substance), Alkylating Agents, Alkylating drugs, Alkylator, Alkylators, Britain-BNF/Mustine (Chlormethine)
Definition

Primarily an Antineoplastic cancer chemotherapy drug; Alkylating agents interfere with methylation of DNA in mitosis, inhibits cell division; Speciality use only is recommended; a dangerous class of drugs with predictable bone marrow suppression often; also used in auto-immune disorders

(Edit)

External Links Related to Alkylating agent Administration/Toxicity
Google
Wikipedia
Merck
Images
PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
Ads