Disease Information for Akinetic mutism

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Clinical Manifestations
Signs & Symptoms
Aphasia
Dysphasia
Disease Mechanism & Classification
Class
CLASS/Neurologic (category)
Process
PROCESS/Vegetative-Autonomic/Endocrine (category)
Definition

A syndrome characterized by a silent and inert state without voluntary motor activity despite preserved sensorimotor pathways and vigilance. Bilateral FRONTAL LOBE dysfunction involving the anterior cingulate gyrus and related brain injuries are associated with this condition. This may result in impaired abilities to communicate and initiate motor activities. (From Adams et al., Principles of Neurology, 6th ed, p348; Fortschr Neurol Psychiatr 1995 Feb;63(2):59-67)

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NEJM (The New England Journal of Medicine)
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