Disease Information for Adult Copper Deficiency Myelopathy

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Clinical Manifestations
Signs & Symptoms
Ataxia
Ataxia/Posterior columns
Bilateral abdominal reflex decreased
Broad based/wide gait
Gait disturbance/abnormality
Lhermittes sign (tingling on neck flex)
Loss deep pain sensation
Loss position sense/postural sense
Paresthesias
Poor coordination legs/feet
Position sense decreased/proprioception
Progressive neurological disorder/signs
Romberg sign positive
Spasticity/Spastic gait
Staggering Gait
Unable to tandem walk/straight line
Vibratory sense decreased
Vibratory sense decreased Legs
Unable to walk/night
Walking difficulties
Clinical Presentation & Variations
Presentation/Progressive Motor Sensory Polyneuropathy
Disease Progression
Course/Progressive
Demographics & Risk Factors
Established Disease Population
Patient/Gastric Bypass
Sex & Age Groups
Population/Adult/all
Laboratory Tests
Abnormal Lab Findings (Non Measured)
Microcytes/small RBCs on Blood smear
Abnormal Lab Findings - Decreased
Ceruloplasmin (Lab)
Copper, serum (Lab)
URINE Copper
Abnormal Lab Findings - Increased
Zinc, serum (Lab)
Diagnostic Test Results
Pathology
PATH/Degeneration lateral/dorsal columns(cord)
CT Scan
MRI/Spinal cord abnormalities
Associated Diseases & Rule outs
Associated Disease & Complications
Adult Copper Deficiency Myelopathy
Paraplegia, spastic
Disease Mechanism & Classification
Class
CLASS/Neurologic (category)
CLASS/Spinal cord disorder (ex)
Pathophysiology
Pathophysiology/Posterior columns cord def
Process
PROCESS/Deficiency (category)
PROCESS/Deficiency/Minerals/Trace metals/Inorganics (ex)
Definition
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External Links Related to Adult Copper Deficiency Myelopathy
Google
Wikipedia
Merck
Images
PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
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