Disease Information for ACTH (Acthar) Administration/Toxicity

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Clinical Manifestations
Signs & Symptoms
Acne flare
Bruising/Ecchymosis
Hirsutism
Hypertrichosis
Striae/Purple striae
Thin skin/parchment-like skin
Buffalo hump
Moon-like facies
Excessive/easy bruising tendency
Truncal obesity
Laboratory Tests
Microbiology & Serology Findings
Stool Microscopic polys present
Abnormal Lab Findings - Decreased
Cholesterol (Lab)
Lymphocytes (Lab)
Abnormal Lab Findings - Increased
WBC
ACTH/Corticotrpin/Adrenocortical Hypertrophic hormone (Lab)
Cortisol (Lab)
Glucose, blood (Lab)
WBC/White Blood Cell Count/Leukocytes (Lab)
Zinc, serum (Lab)
URINE 17-Hydroxycorticosteroids
URINE 17-Ketosteroids
URINE Cortisol/Free Cortisol
URINE Creatine
URINE Free Cortisol/24 Hour
Diagnostic Test Results
Other Tests & Procedures
Skin test anergy
TEST/Decadron suppression abnormal
Pathology
PATH/Adrenocortical hypertrophy
Isotope Scan
Isotope/RAI Uptake low/thyroid scan (I 123)
Isotope/RAI uptake/quantitative high thyroid (I 123)
CT Scan
CT Scan/Adrenal Mass Bilateral
MRI/Bilateral Adrenal Masses/abdomen
Associated Diseases & Rule outs
Associated Disease & Complications
Acne vulgaris (acne)
Anergic status
Corticosteroid effect/toxicity
Cushings, iatrogenic syndrome
Drug induced Hyperglycemia
Hyperglycemia
Hypertension
Iatrogenic corticosteroid/treatment/effects
Leukocytosis
Peptic ulcer disease
Pituitary adenoma, ACTH secreting
Diabetes mellitus/non-insulin dep/type II
Disease Mechanism & Classification
Drugs
DRUG/Biologicals/serums/vaccines/blood products (cat)
DRUG/Cortisone/Corticosteroid drug (ex)
DRUG/Hormonal agent/derivative medication (example)
Process
PROCESS/Medication/Drug (CONFIRM dose/before treatment)
Synonyms
Synonym
1 39 ACTH, ACTH, ACTH Adrenocorticotrophic hormone, ACTH (1 39), ACTH (Hormone), ACTH Adrenocorticotrophic horm, ACTH preparation, admin, Adrenocorticotrophic hormone, Adrenocorticotropic hormone, Adrenocorticotropic hormone (ACTH), Adrenocorticotropic hormone (substance), Adrenocorticotropic hormone preparation, adrenocorticotropic peptide, Adrenocorticotropin, adrenotrophin, adrenotropic hormone, adrenotropin, CCTROP, Corticotrophic hormone, Corticotrophin, Corticotrophin (1 39), Corticotrophins, Corticotrophins (product), Corticotrophins (substance), Corticotropic hormone, Corticotropin, Corticotropin (1 39), CORTICOTROPIN PREPARATION, Corticotropin preparation (product), Corticotropin preparation (substance), Corticotropins, Hormone Adrenocorticotrophic, Hormone Adrenocorticotropic, Brand name/ACTHAR (ACTH), Synonym/Corticotropin administration
Treatment
Drug Dosage
DRUG/Injectable medication (parenteral)
DRUG/Injectable preparation only
DRUG/Intramuscular injection RX
DRUG/Intravenous administraton RX
DRUG/Orally ineffective drug
Definition

natural hormone (pituitary source/bioengineered) stimulates cortisol release from adrenal gland; parenteral preparation

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External Links Related to ACTH (Acthar) Administration/Toxicity
Google
Wikipedia
Merck
Images
PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
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